| Item | Specification |
| Product Name | Snake Tripeptide (Syn-Ake) |
| INCI Name | Dipeptide Diaminobutyroyl Benzylamide Diacetate |
| CAS No. | 823202-99-9 |
| Synonyms | Syn-Ake, Dipeptide Diaminobutyroyl Benzylamide, Snake venom peptide mimic |
| Molecular Formula | C21H37N7O3 · 2C2H4O2 |
| Molecular Weight | 523.67 |
| Amino Acid Sequence | β-Ala-Pro-Dab-NH-Bzl (dipeptide derivative) |
| Appearance | White or off-white lyophilized powder |
| Purity (HPLC) | ≥98.0% |
| Peptide Content | ≥95.0% |
| Water Content (KF) | ≤8.0% |
| Solubility | Soluble in water, aqueous buffer |
| Storage Condition | -20℃, sealed, protected from light and moisture |
| Shelf Life | 24 months under recommended storage |
| Transportation | Room temperature / cool dry shipping, moisture-proof packaging |
Products Description
What is Snake Tripeptide?
Snake Tripeptide, commonly known as Syn-Ake, INCI name Dipeptide Diaminobutyroyl Benzylamide Diacetate, CAS 823202-99-9, is a synthetic cosmetic peptide mimicking the active structure of Waglerin-1 from snake venom. It works by temporarily inhibiting muscle contraction signals to reduce facial expression lines such as crow's feet and forehead wrinkles. Supplied as white or off-white lyophilized powder with excellent water solubility, it is a popular anti-aging active ingredient for skincare formulation development. It is widely used for cosmetic product R&D and related in vitro efficacy testing. Snake Tripeptide is for cosmetic formulation and laboratory research purposes only, not for pharmaceutical or human clinical treatment.
These are mainstream cosmetic anti-aging peptides, classified into neurotransmitter-inhibiting neuropeptides and collagen-stimulating signal peptides. Neuropeptides such as Snake Tripeptide, Argireline and SNAP-8 focus on relaxing facial muscle contraction to fade dynamic expression lines. Matrixyl and GHK-Cu work by stimulating skin matrix synthesis to improve static wrinkles and skin texture. Formulators often combine multiple peptides together to achieve multi-dimensional anti-aging effects. All products are for cosmetic formulation and laboratory research use only.
| Product Name | CAS No. |
| Snake Tripeptide (Syn-Ake) | 823202-99-9 |
| Acetyl Hexapeptide-8 (Argireline) | 616204-22-9 |
| Acetyl Octapeptide-3 (SNAP-8) | 868844-74-0 |
| Pentapeptide-18 (Leuphasyl) | 64577-63-5 |
| Palmitoyl Pentapeptide-4 (Matrixyl) | 214047-00-4 |
| Copper Tripeptide-1 (GHK-Cu) | 49557-75-3 |

Applications of Syn-Ake
Snake Tripeptide (Syn-Ake) is a cosmetic-grade biomimetic peptide widely applied in anti-aging skincare formulation and in vitro cosmetic efficacy research. It mimics the active fragment of snake venom Waglerin-1 to gently inhibit neuromuscular signal transmission, relaxing over-contracted facial muscles and reducing dynamic expression wrinkles such as forehead lines, crow's feet and perioral lines. Formulators incorporate this peptide into serums, essences, creams, eye creams and ampoule products targeting expression line reduction. It can also be used for in vitro cell testing to evaluate muscle relaxation and anti-wrinkle efficacy. This ingredient is favored by cosmetic R&D teams for developing gentle, non-invasive anti-aging skincare products. It is for cosmetic formulation and laboratory research purposes only, not for pharmaceutical or clinical medical use.
Bullet-Point Benefits of Syn-ake
Snake Tripeptide (Syn‑Ake) is a popular biomimetic anti‑wrinkle cosmetic peptide trusted by cosmetic formulators for expression line skincare development. It mimics Waglerin‑1 from snake venom to modulate neuromuscular signals and relax tense facial muscles, helping reduce dynamic wrinkles including crow's feet and forehead lines without aggressive irritation. Supplied as lyophilized powder with ≥98% HPLC purity, it delivers low impurity levels and stable batch consistency to minimize interference during formulation and in‑vitro efficacy tests. This peptide features excellent water solubility, allowing easy integration into aqueous skincare systems such as serums, essences and eye creams. It offers a gentle alternative to harsh anti‑aging actives and can be blended with other cosmetic peptides to create synergistic multi‑peptide formulas. It is suitable for cosmetic R&D laboratories, skincare brand formulation teams and cosmetic raw material distributors.
Packing &Shipping
1.Light-proof & moisture-proof vacuum aluminum foil inner packaging
2.Dry and moisture-proof global shipping
Packaged with desiccants to control humidity, cool and dry transport is recommended.
3.Reinforced shock-resistant outer carton
Sturdy outer box reduces breakage risk during international transit.

CONTACT PAGE
You can purchase cosmetic-grade Snake Tripeptide (Syn-Ake) directly from our company. Submit your inquiry via our contact form, email or WhatsApp to get quotation and technical support. We offer sample and bulk supply with worldwide moisture-proof shipping for cosmetic formulation and lab research.
1.Inquiry methods:
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information:
Name:Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
FAQ
Q: Is Snake Tripeptide water soluble?
A: PYes. Snake Tripeptide lyophilized powder dissolves easily in water and aqueous cosmetic systems. It can be directly added into water-based formulations without harsh organic solvents.
Q: How should I store Snake Tripeptide?
A: Store sealed Snake Tripeptide powder at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles. Shelf life is 24 months under recommended storage. After reconstitution, aliquot the solution and keep refrigerated for short-term use.
Q: What packaging sizes do you offer for Snake Tripeptide?
A: Standard sample sizes:1g,5g,10g vacuum aluminum foil bags. Bulk sizes:20g,100g,500g sealed containers. Custom packaging specifications are available upon request.
Q: Can Snake Tripeptide be mixed with other cosmetic peptides?
A: Yes. Snake Tripeptide has good compatibility with other anti-aging peptides including Acetyl Hexapeptide-8, GHK-Cu and Matrixyl. Combined formulas can achieve synergistic wrinkle-reducing and skin-repairing effects. Formulators need to test stability for each custom formula.
Q: Does Snake Tripeptide cause skin irritation?
A: Snake Tripeptide is a mild biomimetic peptide. Compared with strong neurotoxin ingredients, it has lower irritation risk. However, skin sensitivity varies. It is recommended to complete formula stability and patch testing before mass production for finished skincare products.
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