| Product Name | HGH Fragment 176-191 |
| Cas No. | 66004-57-7 |
| Sequence | somatotropin(176-191);CL233;HGHFragment176-191Trifluoroaceticacid;L-Phenylalanine,L-phenylalanyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-Chemicalbookα-glutamylglycyl-L-seryl-L-cysteinylglycyl-,cyclic(7→14)-disulfide(9CI);HGHFragment176-191(TFAsalt);GrowthHormonePeptideFragmentHGH176-191HghFrag176Aod9604;HGH176-191;HGHfragmentation191-176 |
| Molecular Formula | C78H123N23O22S2 |
| Molar Mass | 3751.202 g/mol |
| Purity | ≥99% |
| Impurity | ≤0.5% |
| Storage Temperature | 2-8ºC |
| Packing Size | 1G/Bottle, 10G/Bottle,50G/Bottle or at customers reqirement. |
Products Description
What is HGH Fragment 176-191?
HGH Fragment 176-191 is a synthetic peptide derived from the 176-191 amino acid sequence of human growth hormone (HGH). Unlike full-length HGH, this fragment retains specific biological activities without affecting IGF-1 levels or insulin sensitivity, making it a subject of interest in research and potential therapeutic applications.

Product COA
Certificate Of Analysis
|
Product Name |
HGH Fragment 176-191 |
CAS No. |
|
|
|
Molecular Formula |
C32H49N9O5 |
Molecular Weight |
1799.1 | |
|
Batch No. |
C172H265N43O51 |
Date of Mfg |
Dec 27,2025 |
|
|
Reference Standard |
Enterprise Standard |
Retest Date |
Dec 26,2028 |
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|
Storage |
In an airtight container,protected from light,at a temperature of 2℃ to 8℃. |
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|
TEST |
SPECIFICATION |
RESULT |
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|
Appearance |
White or almost white fluffy powder |
Conform |
||
|
Solubility |
Soluble in water |
Conform |
||
|
Water Content (Karl Fischer) |
≤ 8.0% |
2.20% |
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|
Sodium ion |
≤ 5.0% |
1.65% |
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|
Acetic Acid |
≤ 0. 1% |
0.07% |
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|
Trifluoroacetic Acid |
≤ 0.5% |
Not Detected |
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|
Peptide Purity (By HPLC) |
≥ 98.0% |
99.32% |
||
|
Related Substance (By HPLC) |
Total Impurities(%) ≤ 2.0% |
0.68% |
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|
Largest Single Impurity(%) ≤ 1.0% |
0.31% |
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|
Bacterial Endotoxins |
≤10EU/mg |
Conform |
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|
Assay |
≥ 90.0% |
94.42% |
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|
Residual Solvents |
NMT 0.041% |
0.03% |
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|
Conclusion |
This batch of product conforms with enterprise standard and qualified. |
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Benefits of HGH Fragment 176-191
1. Weight Management & Fat Loss
Lipolytic Action: Acts as a potent fat burner by stimulating the breakdown of stored triglycerides in adipose tissue, particularly targeting abdominal fat. Studies show it can reduce body fat percentage without causing muscle loss.
Metabolic Regulation: Helps normalize blood glucose levels by enhancing insulin sensitivity in fat cells, supporting healthy metabolism.
2. Joint & Tissue Repair
Cartilage Regeneration: Promotes chondrocyte proliferation and cartilage matrix synthesis, showing potential in treating osteoarthritis and joint injuries.
Muscle Recovery: Accelerates muscle tissue repair after exercise or injury by increasing protein synthesis and reducing inflammation.
3. Anti-Aging Effects
Skin Health: Stimulates collagen and elastin production, improving skin elasticity and reducing the appearance of wrinkles.
Cellular Repair: Enhances mitochondrial function and reduces oxidative stress at the cellular level, supporting overall longevity.
4. Therapeutic Applications
Obesity Treatment: Investigated as a potential adjunct therapy for obesity due to its targeted fat-loss properties without systemic side effects.
Metabolic Disorders: Shows promise in managing type 2 diabetes and metabolic syndrome by improving insulin sensitivity and lipid profiles.
Product Application
1. Clinical Therapeutics
Obesity Management: Investigated as a targeted anti-obesity agent due to its ability to break down stored fat, particularly visceral fat, without inducing muscle wasting. Early clinical trials show it can reduce body fat percentage by 3-5% over 12 weeks in combination with lifestyle modifications.
Metabolic Syndrome: Shows promise in improving lipid profiles and insulin sensitivity, with potential use as an adjunct therapy for type 2 diabetes and non-alcoholic fatty liver disease (NAFLD).
2. Sports and Fitness
Body Composition Optimization: Used off-label by athletes and bodybuilders to reduce subcutaneous fat while preserving lean muscle mass, especially during cutting phases. Its non-suppressive effect on natural testosterone production makes it a preferred alternative to anabolic steroids.
Recovery Enhancement: May accelerate muscle repair and reduce post-workout inflammation by promoting protein synthesis and mitochondrial biogenesis in muscle tissue.
3. Anti-Aging and Regenerative Medicine
Skin Rejuvenation: Stimulates collagen and elastin synthesis, improving skin elasticity and reducing the appearance of wrinkles. Preliminary studies indicate it may enhance wound healing by promoting fibroblast proliferation.
Joint Health: In preclinical models, it has shown ability to protect cartilage from degradation and promote chondrocyte growth, suggesting potential for treating osteoarthritis.
4. Oncology Support
Cachexia Management: Being studied for its ability to reverse muscle wasting in cancer patients by modulating protein metabolism and reducing pro-inflammatory cytokine levels.
Drug Delivery Synergy: May enhance the efficacy of chemotherapy drugs by increasing tumor cell uptake and inhibiting multidrug resistance mechanisms.

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