| Product Name | 99% Purity Medetomidine Hydrochloride CAS 86347-15-1 |
| CAS | 86347-15-1 |
| Appearance | white powder |
| Molecular formula | C13H17ClN2 |
| Molecular Weight | N/A |
| Assay | 99% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
| Synonyms | 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride; Domitor; Metomidine; MPV 785; Zalopine; (r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride; 4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride; medetomidine HCL; 1H-Imidazole, 4-1-(2,3-dimethylphenyl)ethyl-, monohydrochloride; 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1) |
| InChI | InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H |
Products Description
What is Medetomidine Hydrochloride Powder?
Medetomidine hydrochloride is a Off-white to white Pharmaceutical Raw Materials powder.
Medetomidine hydrochloride is a synthetic drug used as both a surgical anesthetic and analgesic.
such as : dogs, cats.
Medetomidine hydrochloride is a potent, orally active α₂-adrenoceptor agonist with high selectivity for α₂ over α₁ receptors (Ki values: 1.08 nM for α₂ vs. 1750 nM for α₁), exhibiting ~1620-fold greater selectivity than α₁-adrenoceptors. As an imidazole derivative, it mimics adrenergic neurotransmitters by activating presynaptic α₂ receptors in the central and peripheral nervous systems, inhibiting norepinephrine release and reducing sympathetic activity.
CAS Number: 86347-15-1
Molecular Formula: C₁₃H₁₇ClN₂
Molecular Weight: 236.74 g/mol
Appearance: Off-white to gray crystalline powder
Solubility: Soluble in water (≥50 mg/mL) and ethanol; slightly soluble in acetonitrile and methanol.
Storage: Store at 4°C (sealed, moisture-free) or -80°C (long-term in solvent).
Product COA
Certificate Of Analysis
|
Product Name |
Medetomidine Hydrochloride | ||
|
CAS No. |
86347-15-1 |
Batch No. |
TK240515 |
|
Molecular Formula |
C13H17ClN2 |
Date of Mfg |
2024.05.16 |
|
Test Standard |
Enterprise Standard |
Date of Exp |
2026.05.15 |
|
Storage |
Keep in dark and cool dry place ,2 to 8℃ |
||
|
Test Items |
Specifications |
Results |
|
Appearance |
White powder |
Complies |
|
Odor |
Characteristic |
Complies |
|
Tasted |
Characteristic |
Complies |
|
Assay |
99% |
Complies |
|
Sieve Analysis |
100% pass 80 mesh |
Complies |
|
Loss on Drying |
5% Max. |
1.02% |
|
Sulphated Ash |
5% Max. |
1.3% |
|
Extract Solvent |
Ethanol & Water |
Complies |
|
Heavy Metal |
5ppm Max |
Complies |
|
As |
2ppm Max |
Complies |
|
Residual Solvents |
0.05% Max. |
Negative |
|
Microbiology |
|
|
|
Total Plate Count |
1000/g Max |
Complies |
|
Yeast & Mold |
100/g Max |
Complies |
|
E.Coli |
Negative |
Complies |
|
Salmonella |
Negative |
Complies |
|
Conclusion:This batch complies with enterprise standard. |
||
Benefits of Medetomidine Hydrochloride Powder
Potent and Selective α₂-Adrenoceptor Agonism
Acts as a highly selective agonist for α₂-adrenergic receptors (Ki = 1.08 nM for α₂ vs. 1750 nM for α₁), offering ~1620-fold greater selectivity over α₁ receptors compared to clonidine, minimizing off-target effects.
Dual Sedative-Analgesic Effects
Induces dose-dependent sedation, analgesia, and anxiolysis, reducing sensitivity to environmental stimuli while providing pain relief without narcotic-related side effects.
Peripheral Vasoconstriction
Activates α₂ receptors on blood vessels, causing transient peripheral vasoconstriction, which may initially increase systemic arterial blood pressure.
Application of Medetomidine Hydrochloride Powder
1. Veterinary Medicine
Sedation & Restraint: Facilitates clinical examinations, minor surgical procedures (e.g., wound treatment), and dental care in dogs, cats, and other animals, where intubation is unnecessary.
Analgesia: Used alone or as an adjuvant to reduce pain during diagnostic or therapeutic interventions.
Muscle Relaxation: Exhibits mild muscle relaxant properties, aiding in handling fractious animals.
2. Research & Pharmacology
Neuropharmacology Studies: Serves as a tool compound to investigate α₂-adrenoceptor-mediated pathways in the central and peripheral nervous systems.
In Vitro/In Vivo Models: Used to study effects on hormone secretion (e.g., inhibits aldosterone release in adrenal cells) and cardiovascular responses (e.g., bradycardia, transient hypertension).
3. Analytical Standards
Available as a reference standard for qualitative/quantitative analysis in pharmaceutical research and quality control.
Safety Considerations
Adverse Effects: May cause respiratory depression, bradycardia, or hypotension at high doses. Reversal agents (e.g., atipamezole) are used to counteract severe effects.
Hazards: Classified as a warning-level substance (H317: May cause an allergic skin reaction; H319: Causes serious eye irritation).
Packaging & Shipping
FAQ
Q: Can I get some samples?
A:Yes, we can provide free samples, but the shipping cost is paid by the customer.
Q: How to start an order or make a payment?
A:The proforma invoice will be sent first after order confirmation, with our bank information enclosed. Payment via wire transfer, Western Union or PayPal, or escrow.
Q: How to confirm product quality before placing an order?
A:You can send us your product specifications and requirements, and we will produce the products according to your requirementsget free samples of some products. , you just need to pay the freight or arrange express delivery to us and then get the sample.
You can send us your product specifications and requirements, and we will produce the products according to your requirements.
Q: Is there any discount?
A:Different quantities have different discounts.
Q: How do you deal with quality complaints?
A:First, our quality control will reduce quality issues to close to zero. If there are real quality problems caused by
us, we will provide you with a free replacement or refund for your lost goods.
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