Premium Promethazine Hydrochloride CAS 58-33-3 for Effective Allergy Relief and Sl

Product name	Promethazine Hcl Hydrochloride prometazina em po Polvo
CAS No.	58-33-3
Molecular formula	C17H21ClN2S
Molecular weight	320.88
EINECS number	200-375-2
Purity	>99% Pure

Promethazine hydrochloride is a first-generation antihistamine drug in powder form, which belongs to the phenothiazine class. It works by blocking the action of histamine, a natural substance in the body that causes allergic symptoms, and also has sedative, antiemetic, and anticholinergic effects. The powder form is often used as an active pharmaceutical ingredient (API) for compounding into various dosage forms like tablets, syrups, injections, or suppositories.

Promethazine Hydrochloride Powder

Product Name	Promethazine Hydrochloride Powder
Chemical Formula	C₁₇H₂₁ClN₂S	Molecular Weight	320.880
CAS	50-28-2	Batch Quantity	400kg
Batch No.	MLP-PPH-20231114	Manufacture Date	2025.11.14
Report Date	2025.11.17	Retest Date	2027.11.13

Testing Items		Specifications	Test Results
BP2010 /EP6	Appearance	crystalline powder	Conforms
	Melting point	About 205°C	206.4°C~206.7°C
	Identification	Meet the requirements	Conforms
	Appearance of solution	Clear, not more intense than Y7	Conforms
	PH	2.4~3.0	2.60
	Loss on drying	≤0.5%	0.04%
	Sulphated ash	≤0.1%	0.01%
	Heavy metals	≤20 ppm	<20 ppm
	Related substances	≤0.25%	Conforms
	Assay	99.0%~101.0%	99.8%
USP32	Identification	Meet the requirements	Conforms
	Loss on drying	≤0.5%	0.04%
	Residue on ignition	≤0.1%	0.01%
	Heavy metals	≤0.003%	<0.003%
	Residue solvent - Ethanol	≤0.5%	<0.04%
	Chloride	16.9%~17.6%	17.1%
	Assay	98.0%~102.0%	100.0%
Conclusion: The product complies with BP2010/USP32/EP6 standard

Antihistamine effect: Inhibits the binding of histamine to H1 receptors, effectively relieving allergic symptoms such as runny nose, sneezing, itchy eyes, skin rashes, and hives.

Sedative and hypnotic effect: Depresses the central nervous system, helping to induce drowsiness and sleep, which is useful for treating insomnia or reducing anxiety before medical procedures.

Antiemetic effect: Blocks dopamine and histamine receptors in the brain's chemoreceptor trigger zone (CTZ), alleviating nausea and vomiting caused by motion sickness, anesthesia, or chemotherapy.

Anticholinergic effect: Reduces smooth muscle spasms and secretions, which can relieve symptoms like cough and stomach cramps.

Allergic conditions: Used to treat seasonal or perennial allergic rhinitis, allergic conjunctivitis, allergic skin reactions, and allergic reactions to blood or plasma products.

Motion sickness: Prevents and treats nausea, vomiting, and dizziness caused by travel (cars, planes, ships, etc.).

Nausea and vomiting: Manages post-operative nausea and vomiting, as well as nausea caused by chemotherapy or radiation therapy.

Sedation and anesthesia: Used as a pre-anesthetic medication to calm patients, reduce anxiety, and enhance the effects of anesthesia. It can also be used for short-term treatment of insomnia.

Cough suppression: Added to some cough syrups to relieve dry, irritating coughs by reducing the cough reflex.

Reproductive system: Breast tenderness, nipple discharge, menstrual irregularities (spotting, amenorrhea)

Gastrointestinal: Nausea, bloating, abdominal cramps

Dermatological: Skin rash, itching, increased pigmentation (especially on face with sun exposure)

Neurological: Headaches, dizziness, mood swings, insomnia

Cardiovascular risks: Chest pain, shortness of breath, sudden severe headache (possible blood clot or stroke)

Malignancy concerns: Unusual vaginal bleeding, breast lumps, persistent pelvic pain (risk of endometrial/breast cancer)

Allergic reactions: Swelling of face/lips/tongue, difficulty breathing, hives

Contraindications: History of hormone-sensitive cancers (breast/uterine), active thromboembolism, liver disease

Monitoring requirements: Regular mammograms, Pap smears, liver function tests

Drug interactions: Avoid with blood thinners, anticonvulsants, and herbal supplements like St. John's Wort

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Alpha-gpc	99%/50%	28319-77-9
5-HTP	99%	56-69-9
CDP-Choline	99%	987-78-0

Oxiracetam	99%	62613-82-5
NSI-189	99%	1270138-40-3
Sunifiram	99%	314728-85-3
Unifiram	99%	272786-64-8
Pramiracetam	99%	68479-62-1
Piracetam	99%	7491-74-9
Agomelatin	99%	138112-76-2

Delivery Time:Around 3-5 workdays after your payment.

Package:1kg/aluminium foil bag;25Kgs in fiber-drums with two-plastic bags inside

Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum

Drum Size & Volume:I.D.42cm × H52cm,0.08 m³/Drum

Storage:Stored in dry and cool place,keep away from strong light and heat.

Shelf Life:Two years when properly stored.

Package	1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
Transit	Fedex, TNT,DHL,EMS,and so on.
Shipping port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	1-2 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

Q: 1. I want to know more details about the product, how can I contact you?

A: You can send us an email inquiry at any time. For more accurate quotes, I need the following information: product name, order quantity, receipt country, quality requirements, etc.

Q: 2. How do I know if your products are real or fake?

A: We will inspect every shipment. I can provide test reports including HPLC, MS and HNMR if you want. Please find a professional chemist to help you confirm the authenticity of the test report.
Of course, you can also purchase samples to take you around your trust.

Q: 3. How do you ensure the safety of the package I receive?

A: I want to receive the package safely, I first need to know your delivery address, do you have a preferred courier method, did you buy it from China?
Why do you want to know?
Because each country has different requirements for imported packages, especially chemical products, you need to know the basic information to provide you with the safest choice.
At present, we have professional customs clearance agents in EU countries, the United States, the United States, Canada, and Southeast Asia. We have professional customs clearance agents to ensure the safety of packages.

Q: 4. How to pay?

A: Our payment channels include bittoin, bank card, Western Union, Allegitudes, etc.
It is usually recommended that customers pay with Bitcoin, because the fee is low, the entry speed is fast, and the security is guaranteed.

Q: 5. How long does it take to receive the package?

A: This will vary according to the delivery method you choose. I will briefly introduce our commonly used special lines.
Usually European countries 10-15 days after sending you the tracking number.
In the United States and Canada, it usually takes 7-10 days.
Southeast Asian countries are 3-7 days.

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