| Product Name | IGF-1 LR3 Powder |
|
CAS No. |
946870-92-4 |
|
Other Names |
IGF-1 LR3;CL281 |
|
MF |
N/A |
|
Place of Origin |
China |
|
Purity |
99% |
|
Appearance |
White powder |
|
Usage |
Cosmetic Raw Materials, Detergent Raw Materials, Hair Care Chemicals, Oral Care Chemicals |
|
Apperance |
White powder |
|
Grade |
Comestic Grade |
|
Shelf life |
2 Years |
Products Description
What is IGF-1 LR3?
[Mechanism of action]
IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.IGF-1 LR3 obstructs the movement of glucose into the body's cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a life in the body for about 20-30 hours and therefore enhance the growth amount of muscle for a whole day.
[Structure]
IGF-1 LR3 is a recombinant synthetic growth factor of ~9.1 kDa, a single polypeptide chain containing 83 amino acid residues. It is an analog of IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid and a 13 amino acid length N terminus peptide extension. It has been engineered for higher biological potency in vitro, with an increased half-life. This recombinant IGF-1 LR3 product is a highly potent growth factor ideal for stem cell research and cell manufacturing applications, including cells of the ectoderm linage (oligodendrocytes, motor neurons) and mesoderm linage (osteocytes, chondrocytes, and muscle cells).
Product COA
Certificate Of Analysis
|
Product Name |
IGF-1 LR3 |
CAS No. |
946870-92-4 |
|
Molecular Formula |
/ |
Molecular Weight |
/ |
|
Batch No. |
XR23110801-6 |
Date of Mfg |
Dec 27,2025 |
|
Reference Standard |
Enterprise Standard |
Retest Date |
Dec 26,2028 |
|
Storage |
In an airtight container,protected from light,at a temperature of 2℃ to 8℃. |
||
|
TEST |
SPECIFICATION |
RESULT |
|
|
Appearance |
White or almost white fluffy powder |
Conform |
|
|
Solubility |
Soluble in water |
Conform |
|
|
Water Content (Karl Fischer) |
≤ 8.0% |
2.20% |
|
|
Sodium ion |
≤ 5.0% |
1.65% |
|
|
Acetic Acid |
≤ 0. 1% |
0.07% |
|
|
Trifluoroacetic Acid |
≤ 0.5% |
Not Detected |
|
|
Peptide Purity (By HPLC) |
≥ 98.0% |
99.32% |
|
|
Related Substance (By HPLC) |
Total Impurities(%) ≤ 2.0% |
0.68% |
|
|
Largest Single Impurity(%) ≤ 1.0% |
0.31% |
||
|
Bacterial Endotoxins |
≤10EU/mg |
Conform |
|
|
Assay |
≥ 90.0% |
94.42% |
|
|
Residual Solvents |
NMT 0.041% |
0.03% |
|
|
Conclusion |
This batch of product conforms with enterprise standard and qualified. |
||
Core Functions & Effects
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).
The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).
Key Applications
Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation
Side effects
Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.
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FAQ
Q1. What is the ordering process for the product?
Answer: Please tell us the specific product and quantity you need, provide your shipping information, select the payment method, and we will arrange the shipment for you as soon as possible after the payment is successful.
Q2. Do you have a minimum order quality?
Answer: Yes, our minimum order quality is one boxes, and of course you can contact us if you need less.
Q3. What is the price of the product?
Answer: Our price changes with the international market. An updated price list will be provided when you contact us.
Q4. How to make the payment?
Answer: We can accept Western Union, Bitcoin, Ali baba, Credit Card, Bank Transfer and other payment methods available.
Q5. When will you deliver the goods?
Answer: After receiving the remittance, we will arrange the delivery for you as soon as possible. The tracking number will be provided to you within 3 days.
Q6. How will you deliver the goods?
Answer: We have professional express forwarder, strong cooperate with DHL, UPS, USPS, FedEx, EMS, China Air Post.
Q7. When will we receive the goods?
Answer: We will send by DHL/FEDEX/UPS/USPS express, usually it takes about 7-15 days to reach you.
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