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Product Name |
Aviptadil Acetate |
|
Appearance |
White to off-white powder |
|
Assay |
99% by HPLC |
|
Molecular Formula |
C147H238N44O42S |
|
CAS Number |
40077-57-4 |
|
Solubility |
H2O/DMSO |
|
Storage |
Cool dry place( Store at -20°C, away from the light) |
Products Description
What is Aviptadil Acetate peptide?
Chemically speaking, it is a polypeptide composed of 28 amino acids with a molecular weight of approximately 3385.9. As an analog of VIP, it simulates all the physiological functions of VIP, especially its powerful vasodilation effect.
Or you can understand it as a key "signaling molecule" that can bind to receptors on specific cells of the body (especially type II alveolar cells in the lungs) to play a protective and regulatory role.
Xi 'an Tongze can provide other peptide products, the catalog is as follows, welcome to consult!
|
Product Name |
CAS No. |
|
Goralatide |
127103-11-1/120081-14-3 |
|
ARA-290(Cibinetide) |
1208243-50-8 |
|
N-acetyl Semax Amidate |
2920938-90-3 |
|
N-AC-selank-amidate |
N/A |
|
Aviptadil Acetate |
40077-57-4 |
|
GLP-1(1-37) |
87805-34-3 |
|
GIP (huMan) |
100040-31-1 |
|
N-Acetyl-Semax |
N/A |
|
N-Acetyl Selank |
N/A |
|
S-Phenylacetyl Larazotide |
N/A |
|
Dermorphin |
77614-16-5 |
|
PEG-MGF |
N/A |
|
Met-enkephalin |
58569-55-4 |
|
Pramlintide Acetate |
196078-30-5 |
|
Dalargin |
81733-79-1 |
|
Abaloparatide |
247062-33-5 |
|
N-Acetyl Larazotide |
N/A |
|
Humanin |
330936-69-1 |
|
Adamax |
N/A |
COA of Aviptadil Acetate peptide
|
Product Name |
Aviptadil Acetate |
CAS Number |
40077-57-4 |
|
Manufacture Date |
2025/09/03 |
Expiration Date |
2027/09/02 |
|
Batch Number |
TZ20250703 |
Batch Quantity |
2020G |
|
Item |
Specification |
Results |
|
Organoleptic Data |
||
|
Appearance |
White to off-white powder |
White powder |
|
Odor &Taste |
Characteristic |
Conform |
|
Identification
|
"HNMR Conforms to structure |
Conform |
|
LCMS Conform to MW |
Conform |
|
|
Physical Characteristics |
||
|
Purity (By HPLC) |
≥99.0% |
99.98% |
|
Loss on drying |
≤0.5% |
0.18% |
|
Residue on ignition |
≤0.2% |
0.13% |
|
Heavy Metal |
≤10ppm |
<10ppm |
|
Lead(Pb) |
≤0.5ppm |
<0.05ppm |
|
Arsenic(As) |
≤1.5ppm |
<0.005ppm |
|
Cadmium(Cd) |
≤0.5ppm |
<0.005ppm |
|
Mercury(Hg) |
≤3.0ppm |
No Detected |
|
Conclusion |
The product conforms with enterprise standard and qualified |
|
|
Storage |
Store in a well closed and dry place with room temperature and no direct sun light. |
|
|
Shelf life |
2 Years When Stored properly |
|
Application of Aviptadil Acetate peptide
Aviptadil acetate is a synthetic peptide analog of Vasoactive Intestinal Polypeptide (VIP) -7. It works by activating VPAC1 and VPAC2 receptors, which are found in high concentrations on alveolar type II (ATII) cells in the lungs -2-8. This activation leads to vasodilation, anti-inflammatory effects, and protection of alveolar cells against injury -2-8.
The table below summarizes the primary applications and their current development status.
| Application Area | Specific Condition | Key Development Status / Details |
|---|---|---|
| Respiratory Distress | Acute Respiratory Distress Syndrome (ARDS) | • FDA Orphan Drug Designation (2005) -1-6 • Investigated for viral and non-viral causes -3 |
| COVID-19 Respiratory Failure | • FDA Fast Track Designation -2-8 • Investigated as ZYESAMI™ (IV and inhaled) to prevent progression to critical respiratory failure -1-10 • A Phase II trial showed faster recovery and reduced lung damage -5 |
|
| Vascular Conditions | Pulmonary Arterial Hypertension (PAH) | • FDA Orphan Drug Designation (2005) -4-6 • Has been investigated as an inhalable therapy -9 |
| Other Investigational Uses | Pulmonary Fibrosis | • Potential to inhibit fibrosis progression -7 |
| Sarcoidosis | • EMEA Orphan Drug Designation -2-8 • Has undergone Phase 2 trials -2 |
|
| Approved (Non-Respiratory) | Erectile Dysfunction | • Approved in Scandinavia and several European countries (co-formulated with phentolamine) |
Safety and Side Effects of Aviptadil Acetate peptide
Aviptadil has generally demonstrated a favorable safety profile in clinical trials.
- Common Side Effects: The only statistically significant adverse event reported is mild to moderate diarrhea (30% in treated participants vs. 1.5% in the placebo group, p<.001) -2-8.
- Other Effects: Systemic hypotension (low blood pressure) was observed but at rates similar to the placebo group (25% vs. 18.5%, P=NS) -2-8.
- Tolerability: Healthy volunteer studies show that IV infusion is well-tolerated with few effects on blood pressure, heart rate, or ECG
Important Notice
Approved Status: While Aviptadil is approved for erectile dysfunction in some European countries, its use for ARDS, COVID-19, and PAH remains investigational or has not received final FDA approval for those indications -1-4. A Phase II/III trial for inhaled Aviptadil in severe COVID-19 is listed as "terminated" -2-10.
Research Use Only: Aviptadil Acetate powder available from chemical suppliers is strictly for preclinical research and laboratory use only and is not for human therapeutic use
Packing & Shipping
Customer Feedback
CONTACT PAGE
1.Inquiry methods：
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information：
Name：Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
FAQ
Q: Can we offer Related products of Aviptadil Acetate peptide?
A: Yes, We can provide other peptides,welcome to consult.
Q: How do you treat quality complaint ?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:Can customized packaging be carried out of Aviptadil Acetate peptide?
A:Of course, it can be repackaged. For instance, it is commonly used in vials or freeze-dried powder bottles for beauty purposes. We can provide them all.
Q:Is there a discount?
A:Of course, welcome to contact us. Price would be different based on different quantity. For bulk quantity, we will have discount for you.At the same time, we have a detailed list of discounted products and products with large inventory every quarter.
Q:Whether customized services can be provided
A:We offer ODM/OEM services and can manufacture according to specified formulations. We have our own designers who can design and customize private brands, packaging. Our customized service from the production of raw materials, design of brands/packaging, to the production of customized packaging, and then to packaging, mailing packages, one-stop production line, welcome to visit.
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