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Product Name |
Bivalirudin powder |
|
Appearance |
White to off-white crystalline powder |
|
Assay |
99% by HPLC |
|
Molecular Formula |
C98H138N24O33 |
|
CAS Number |
128270-60-0 |
|
Solubility |
Easy soluble in organic solvents (e.g., DMSO, ethanol). Low solubility in aqueous solutions; typically requires preparation of stock solutions in DMSO. |
|
Storage |
Cool dry place( Store at -20°C, away from the light) Wear appropriate personal protective equipment during operation to avoid inhalation or direct skin contact. |
Products Description
What is BAM15 peptide?
SBAM15 is a synthetic, small-molecule compound that is neither a "polypeptide" nor a "peptide." It functions as a mitochondrial proton carrier uncoupler. By directly targeting mitochondria-the core organelle of cellular energy metabolism-it represents an "energy-depletion" anti-obesity strategy. Despite promising preclinical data, critical questions regarding human safety, long-term side effects, and optimal dosage remain unknown "black boxes." The journey from laboratory to pharmacy remains exceptionally long. Therefore, any current products containing BAM15 are strictly for scientific research purposes only.
Xi 'an Tongze can provide other peptide products, the catalog is as follows, welcome to consult!
|
Product Name |
CAS No. |
|
Goralatide |
127103-11-1/120081-14-3 |
|
ARA-290(Cibinetide) |
1208243-50-8 |
|
N-acetyl Semax Amidate |
2920938-90-3 |
|
N-AC-selank-amidate |
N/A |
|
Aviptadil Acetate |
40077-57-4 |
|
GLP-1(1-37) |
87805-34-3 |
|
GIP (huMan) |
100040-31-1 |
|
N-Acetyl-Semax |
N/A |
|
N-Acetyl Selank |
N/A |
|
S-Phenylacetyl Larazotide |
N/A |
|
Dermorphin |
77614-16-5 |
|
PEG-MGF |
N/A |
|
Met-enkephalin |
58569-55-4 |
|
Pramlintide Acetate |
196078-30-5 |
|
Dalargin |
81733-79-1 |
|
Abaloparatide |
247062-33-5 |
|
N-Acetyl Larazotide |
N/A |
|
Humanin |
330936-69-1 |
|
Adamax |
N/A |
COA of BAM15 peptide
|
Product Name |
Bivalirudin powder |
CAS Number |
128270-60-0 |
|
Manufacture Date |
2025/08/03 |
Expiration Date |
2027/08/02 |
|
Batch Number |
TZ20250803 |
Batch Quantity |
1000G |
|
Item |
Specification |
Results |
|
Organoleptic Data |
||
|
Appearance |
White to off-white crystalline powder |
White powder |
|
Odor &Taste |
Characteristic |
Conform |
|
Identification |
H-NMR |
Conform |
|
Solubility |
Soluble in water ≥100mg/m (H2O) |
Conform |
|
PH |
4.0-6.0 |
5.85 |
|
Physical Characteristics |
||
|
Purity (By HPLC) |
≥99.0% |
99.78% |
|
Water Content (Karl Fischer) |
≤0.5% |
0.1% |
|
Residual solvent |
Mlethanol≤0.2% |
No Detected |
|
Acetonitrile≤0.2% |
No Detected |
|
|
Triethylamine≤0.2% |
No Detected |
|
|
Bacterial endotoxin |
<10EU/mg |
<0.1EU/mg |
|
Total mold and yeast count |
<10cfu/g |
Conform |
|
Escherichia coli |
<10cfu/g |
No Detected |
|
Total aerobic bacteria |
<10cfu/g |
Conform |
|
Conclusion |
The product conforms with enterprise standard and qualified |
|
|
Packing |
Keep in dark and cool dry place ,2 to 8°C |
|
|
Storage |
Keep in dark and cool dry place |
|
|
Shelf life |
2 Years When Stored properly |
|
Application of BAM15 peptide
Bivalirudin is a direct thrombin inhibitor (DTI) used primarily as an anticoagulant (blood thinner) to prevent clot formation during cardiovascular procedures -1-4-5. Its applications are divided into FDA-approved indications, off-label uses, and special populations.
1. FDA-Approved Indications (Core Applications)
Bivalirudin is FDA-approved for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI) -6-8. This includes several specific clinical scenarios:
| Indication | Details |
|---|---|
| Percutaneous Coronary Intervention (PCI) | Includes procedures such as coronary angioplasty (PTCA) and stent placement -2-6. |
| Unstable Angina / Non-ST Elevation Myocardial Infarction (UA/NSTEMI) | For patients planned for urgent or early intervention -4. |
| ST-Elevation Myocardial Infarction (STEMI) | For patients undergoing primary PCI (emergency procedure to open blocked arteries) -4-8. |
| Heparin-Induced Thrombocytopenia (HIT) / HITTS | Specifically indicated for patients with a history of HIT or HITTS (a serious immune reaction to heparin) who require PCI -2-6-8. |
2. Off-Label and Emerging Applications
Beyond its approved uses, bivalirudin is increasingly used off-label as an alternative anticoagulant in situations where heparin is problematic or ineffective -3-7.
Extracorporeal Membrane Oxygenation (ECMO)
Bivalirudin is used as an alternative anticoagulant for patients requiring ECMO support, a life-support machine for severe heart or lung failure -3-7.
- Why used: Heparin is the standard anticoagulant for ECMO, but it carries a risk of HIT and can be unpredictable in critically ill patients. Bivalirudin provides a more stable anticoagulation profile and is safe in HIT patients -7.
- Key evidence: A large retrospective study of 424 patients on ECMO showed lower mortality in the group receiving bivalirudin compared to heparin -3. Other studies have reported fewer major bleeding events and reduced need for blood transfusions with bivalirudin -3.
- COVID-19 patients: Bivalirudin has been successfully used for anticoagulation in COVID-19 patients requiring ECMO, particularly due to the hypercoagulable state and increased HIT risk in this population -3.
Benefits of Bivalirudin
Bivalirudin demonstrates superior efficacy in reducing major bleeding events across both PCI and ECMO settings, with consistent evidence supporting a 22–69% reduction in bleeding complications. When used with an extended post-PCI infusion, bivalirudin also provides comparable or improved ischemic protection compared to heparin, including reduced stent thrombosis rates. In ECMO patients, bivalirudin shows additional benefits in reducing thrombotic events and in-hospital mortality.
The optimal use of bivalirudin requires:
- In PCI: Extended post-procedure infusion (2–4 hours) to mitigate stent thrombosis risk
- In ECMO: Close aPTT monitoring; rapid attainment and stable therapeutic levels are achievable
- Patient selection: Particularly beneficial in patients at high bleeding risk or with the HIT.
Why Bivalirudin Works ?
Bivalirudin is a direct thrombin inhibitor (DTI) that offers several pharmacological advantages over heparin:
- Direct action: Binds directly to thrombin without requiring antithrombin as a cofactor, providing more predictable anticoagulation -3
- Inhibits clot-bound thrombin: Unlike heparin, bivalirudin inhibits both circulating and fibrin-bound thrombin, which is clinically important because clot-bound thrombin remains enzymatically active and promotes thrombus growth -3.
- Short half-life: ~25 minutes, allowing rapid reversal after discontinuation.
- No risk of HIT: Does not cause heparin-induced thrombocytopenia.
Packing & Shipping
Why Choose Us
Customer Feedback
CONTACT PAGE
1.Inquiry methods：
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information：
Name：Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
FAQ
Q: Can we offer Related products of Bivalirudin?
A: Yes, We can provide other peptides,welcome to consult.
Q: How do you treat quality complaint ?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:Can customized packaging be carried out of Bivalirudin?
A:Of course, it can be repackaged. For instance, it is commonly used in vials or freeze-dried powder bottles for beauty purposes. We can provide them all.
Q:Is there a discount?
A:Of course, welcome to contact us. Price would be different based on different quantity. For bulk quantity, we will have discount for you.At the same time, we have a detailed list of discounted products and products with large inventory every quarter.
Q:Whether customized services can be provided
A:We offer ODM/OEM services and can manufacture according to specified formulations. We have our own designers who can design and customize private brands, packaging. Our customized service from the production of raw materials, design of brands/packaging, to the production of customized packaging, and then to packaging, mailing packages, one-stop production line, welcome to visit.
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