Adenosine 3',5'-cyclic Monophosphate

Adenosine 3',5'-cyclic monophosphate (cAMP) is an important substance involved in regulating substance metabolism and biological functions within cells, serving as the "second messenger" for the transmission of life information.It widely present in animal, plant, and microbial cells.

Its composition is linked by 3 ', 5' - cyclic phosphodiester bonds to the 3 'and 5' carbon atoms of ribose, forming a cyclic structure. The cyclic structure endows it with stability, avoiding hydrolysis by ordinary phosphatases, but it is sensitive to acid and easily hydrolyzed by phosphodiesterase to 5 '- AMP, leading to inactivation. Belonging to polar molecules, easily soluble in water, and capable of free diffusion within the cytoplasm.

Our Xi'an Tongze Biotechnology mainly produces pharmaceutical grade products. The following is the production process diagram

1. Used in Health Care Product
Due to its easy degradation and low oral absorption rate, health supplements usually do not directly add cAMP and need to be mixed with other ingredients to make capsules and functional drinks.
Commonly used cardiovascular health products are mixed formula with fish oil (Omega-3) and Green Tea Extract (Tea polyphenols) to make capsules. This formula is also highly recommended to our customers in the United States and the United Kingdom, and has a wide audience.

2. Used in Food additives
It added to fermented foods, meat products, high protein meal replacement powders, and pickled foods.
Adding it to pickled vegetables can inhibit spoilage bacteria and extend shelf life.
Adding it to the sake brewing process enhances its taste and shortens the fermentation period

1.Regulation of energy metabolism

By activating phosphorylated glycogen phosphorylase kinase, promote glycogen breakdown and inhibit synthase.

The audience is often marathon runners and patients with diabetes. When marathon athletes take energy gummies containing ginsenosides and ribose, their blood sugar levels will rise, which can promote liver glycogen breakdown and improve athletes' endurance.

2.Accelerate the breakdown of fat

It can reduce hormone sensitivity, lipase activity, and fat mobilization. Hormone sensitive triglyceride lipase can directly act on fats, promoting the breakdown of triglycerides into free fatty acids.

If you are in the fitness industry, drinking beverages containing 150mg of green tea extract EGCG 150mg and caffeine 100mg can increase the proportion of fat supply during exercise and accelerate fat burning.

3.Enhance neurocognition

The increase of cAMP can activate protein kinase A, which in turn phosphorylates CREB transcription factor, enabling it to bind to CRE and promote gene transcription. Thus promoting brain-derived neurotrophic synthesis, enhancing neuronal survival and synaptic plasticity. Therefore, it can enhance memory and stress brain protection.

Programmers working in the IT industry who feel stressed can take functional drinks containing phosphatidylserine 100mg and caffeine 50mg, which can lower cortisol levels, relax their nerves, and reduce stress.

Students have heavy academic workload, taking extracts containing fake purslane can increase memory and improve efficiency in completing tasks. Attention should be paid to following medical advice when taking such products.

4.Balance immune inflammation

It inhibits the NF - κ B inflammatory pathway and reduces the release of pro-inflammatory factors such as TNF - α and IL-6.

For pollen allergy patients, it can alleviate allergic reactions, such as reducing the frequency or frequency of sneezing. For chronic inflammation control, such as in arthritis patients, it can reduce the pain of joint swelling.

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