| Product Name: | O-304 |
| CAS: | 1261289-04-6 |
| MF: | C16H11Cl2N3O2S |
| MW: | 380.25 |
| EINECS: | |
| Mol File: | 1261289-04-6.mol |
| Storage | Dry, dark and at 0-4C for short term(days to weeks), or -20C for long term(months to years) |
| Solubility | Soluble in DMSO |
|
Place of Origin |
China |
|
Purity |
99% |
|
Usage |
Cosmetic Raw Materials, Detergent Raw Materials, Hair Care Chemicals, Oral Care Chemicals |
|
Apperance |
White powder |
|
Grade |
Pharmaceutical Grade |
|
Shelf life |
2 Years |
Products Description
What is O-304 CAS 1261289-04-6 ATX-304 Powder?
O-304 (CAS No. 1261289-04-6) is a novel, first-in-class, orally bioavailable pan-AMPK activator widely used in biomedical research and pharmaceutical preclinical studies. Also known as 4-chloro-N-(2-(4-chlorobenzyl)-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)benzamide, this compound effectively activates AMP-activated protein kinase (AMPK) by inhibiting the dephosphorylation of phosphorylated AMPK, delivering stable and significant biological activity.
As a critical research chemical and drug candidate material, O-304 shows excellent potential in studying type 2 diabetes, insulin resistance, and cardiovascular complications. We provide high-purity O-304 powder with strict quality control, complete test reports, and flexible packaging solutions to meet global laboratory and pharmaceutical research demands.
Product COA
Certificate Of Analysis
|
Product Name |
O-304 Powder |
|
|
|
Molecular Formula |
C16H11Cl2N3O2S |
||
|
Cas No. |
1261289-04-6 |
Quantity |
1400KG |
|
MFG. Date |
2025.04. 11 |
Batch No |
MLP-PEA-20250411 |
|
Report Date |
2025.04. 17 |
Retest Date |
2027.04. 10 |
|
Testing Items |
Specifications |
Results |
|
Appearance |
Fine white to off-white crystal powder |
Conforms |
|
Color |
White to Off-white |
Conforms |
|
Identification |
NMR |
Conforms |
|
Loss on Drying |
≤ 1.0% |
0.24% |
|
Water |
≤ 1.0% |
0. 17% |
|
Residue on ignition |
≤ 0. 10% |
0.06% |
|
Purity (HPLC) |
≥ 99.0% |
99.51% |
|
Heavy metal |
||
|
Lead(Pb),mg/kg |
≤ 0.5 |
Conforms |
|
Total arsenic(As), mg/kg |
≤ 0. 15 |
Conforms |
|
Cadmium(Cd),mg/kg |
≤ 2.5 |
Conforms |
|
Total mercury(Hg), mg/kg |
≤ 1.5 |
Conforms |
|
Solvent residue |
||
|
Methanol |
≤ 0.3% |
Not detected |
|
Ethanol |
≤ 0.5% |
Not detected |
|
Ethyl acetate |
≤ 0.5% |
Not detected |
|
Microbiological control |
||
|
Total Plate Count |
≤ 10,000cfu/g |
Conforms |
|
Yeast & Mold |
≤ 300cfu/g |
Conforms |
|
Coliforms |
≤ 10cfu/g |
Conforms |
|
E.Coli |
Negative/10g |
Conforms |
|
Salmonella sp. |
Negative/25g |
Conforms |
|
Staph Aureus |
Negative/10g |
Conforms |
|
Pseudomonas aeruginosa |
Negative/25g |
Conforms |
|
Conclusion |
Conform with the in-house standard |
|
|
Packing and Storage |
||
|
Packing |
Pack in paper-drums and PE bags inside. 25Kg/Drum |
|
|
Storage |
Store in a well-closed container away from moisture and direct sunlight |
|
Core Product Specifications
|
Item |
Specification |
|---|---|
|
Product Name |
O-304 |
|
CAS Number |
1261289-04-6 |
|
Molecular Formula |
C₁₆H₁₁Cl₂N₃O₂S |
|
Molecular Weight |
380.25 |
|
Appearance |
White Crystalline Powder |
|
Purity |
≥98% / 99.84% (HPLC Test) |
|
Solubility |
Soluble in organic solvents, slightly soluble in water |
|
Synonyms |
ATX-304, 4-chloro-N-(2-(4-chlorobenzyl)-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)benzamide |
Key Advantages of Our O-304
Oral Bioavailability: The compound features excellent oral absorption properties, making it ideal for in vivo animal experiments and preclinical drug development research, avoiding the limitations of injection-only activators.
Complete Documentation Support: We provide professional COA, HPLC spectrum, MSDS, and technical datasheets for every batch, supporting global customer laboratory audits and research project filing.
Flexible Packaging & Fast Delivery: Available in multiple specifications (2mg, 5mg, 10mg, 25mg, 50mg, 100mg, bulk order). We support customized packaging and global fast shipping with stable inventory supply.
Applications & Research Fields
O-304 (CAS 1261289-04-6) is a high-value research compound widely applied in modern biomedical and pharmacological research, mainly covering the following fields:
Metabolic Disease Research: Core material for studying type 2 diabetes mellitus, improving hyperglycemia, and alleviating insulin resistance.
Cell Metabolism Research: Regulates cellular energy metabolism, promotes glucose and lipid catabolism, and supports research on obesity and metabolic syndrome.
Drug Candidate Development: Serves as a leading compound for the development of new oral hypoglycemic and metabolic regulation drugs.
Storage & Handling Instructions
Storage Condition: Store in a cool, dry, dark and ventilated place, sealed tightly at 2-8℃ for long-term preservation.
Shelf Life: 24 months under professional sealed storage conditions.
We are a professional global supplier of high-purity biochemical research compounds. For O-304 CAS 1261289-04-6, we guarantee batch-to-batch consistency, strict quality inspection, and competitive factory prices. We support sample testing, small-batch trial orders, and large-batch customized production. Professional technical teams provide 24/7 online consulting services to solve your product selection, usage and technical problems.
Handling Notes: Avoid direct contact with skin and eyes; wear professional protective gloves and goggles during operation. Keep away from moisture and high temperature environment to prevent product deterioration.
Contact us now to get the latest quotation, free sample and complete product technical documents!
Packaging & Shipping
|
Weight |
Packing method |
|
1kg |
bag/kg, box outside (double plastic bag + Aluminum foil bag inside) |
|
10kgs,25kg or more |
by Drums or carton (3 layers plastic bag inside) |
|
Weight |
Delivery mothod |
Delivery time |
|
1kg-25kgs |
EMS,DHL,UPS,Fedex,TNT |
3-7days |
|
25kgs-100kgs |
DHL,FedEx,by Air |
3-7days |
|
more than 100kgs |
by Air |
3-7days |
|
by Sea |
10-35days |
FAQ
Q: 1. Who are we?
A: We are based in Shandong, China, start from 2020,sell to Domestic Market(45.00%),Western Europe(10.00%),Eastern Asia(10.00%),North America(10.00%),Africa(5.00%),Central America(5.00%),Southeast Asia(5.00%),South America(5.00%),Mid East(5.00%). There are total about 51-100 people in our office.
Q: 2. How can we guarantee quality?
A: Always a pre-production sample before mass production; Always final Inspection before shipment;
Q: 3. What can you buy from us?
A: Fluorescent whitening agents, pigments and dyes, pharmaceutical intermediates, paint decoration, pharmaceutical impurities and other products.
Q: 4.Why should you buy from us not from other suppliers?
A: RD &marketing experience products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.
Q: 5.What services can we provide?
A: Accepted Delivery Terms: FOB,CFR,CIF,EXW,FAS,CIP,CPT,DDU,Express Delivery; Accepted Payment Currency:USD,EUR,CNY; Accepted Payment Type: T/T,L/C,D/P D/A,Western Union,Cash; Language Spoken:English,Chinese.
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