Azithromycin Powder API

Azithromycin is the second generation of major cyclolactone drugs, which are used to treat respiratory and reproductive tract infections. To treat a variety of pathogens causing respiratory tract infection of children and adults, genital tract chlamydia trachomatis infection, etc., and been to many countries and regions in medical guidelines recommend recommended as the first-line treatment of infection drugs (such as the United States, Japan, the United States and China.

Antibacterial effect:
Mechanism of action: Combining with the bacterial 50S ribosomal subunit, it inhibits peptide chain elongation and blocks protein synthesis (belonging to antibacterial agents, can kill bacteria at high concentrations).
Antibacterial spectrum:
Gram positive bacteria: Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus (methicillin-resistant strains).
Gram negative bacteria: Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae.
Atypical pathogens: Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila.
Other: Chlamydia trachomatis (used for sexually transmitted infections), Mycobacterium avium complex (MAC, used for immunosuppressed patients).
Anti inflammatory and immune regulatory effects:
In chronic respiratory diseases such as COPD and bronchiectasis, airway inflammation may be alleviated by inhibiting inflammatory factors such as IL-8 and TNF - α.

Inhibit the synthesis of bacterial protein and exert strong bacteriostatic and bactericidal effects.

Wide antibacterial spectrum, effective against Gram-positive bacteria, Gram-negative bacteria and some atypical pathogens.

Long half-life, less side effects and good tissue penetration.

Relieve inflammation and eliminate infectious lesions rapidly.

Treat respiratory tract infections: pharyngitis, tonsillitis, bronchitis, pneumonia, sinusitis.

Cure urinary and reproductive system infections such as urethritis and cervicitis.

Treat skin and soft tissue bacterial infections.

Used for otitis media, tonsillitis and pediatric bacterial infections.

Applied in veterinary medicine and pharmaceutical intermediate preparation.

Respiratory infection:
Community acquired pneumonia (CAP), acute exacerbation of chronic bronchitis, acute otitis media, sinusitis.
Pertussis (as an alternative treatment).
Skin and soft tissue infections: cellulitis, erysipelas (targeting streptococci or sensitive staphylococci).
Sexually transmitted infections (STIs):
Non complicated urethritis/cervicitis (caused by Chlamydia trachomatis or Neisseria gonorrhoeae).
Soft chancre (combined with other medications).
other:
Prevention and treatment of Mycobacterium avium complex (MAC) infection in HIV/AIDS patients.
Traveler's diarrhea (caused by Escherichia coli or Campylobacter).

Pharmacokinetic characteristics
Oral absorption: The bioavailability is about 37%, and food can reduce absorption (recommended to be taken on an empty stomach).
Organizational distribution:
Rapid infiltration into tissues, with significantly higher concentrations in areas such as the lungs, tonsils, and prostate than in plasma.
Half life of up to 68 hours, supports short course treatment (such as 3-day or 5-day regimen).
Metabolism and excretion:
Mainly metabolized by the liver as inactive products, excreted through bile (about 50%), and a small amount excreted through the kidneys.
Patients with renal insufficiency generally do not need to adjust the dosage, and those with severe liver disease should use it with caution.
 

Dosage Forms: It is frequently dispensed as multi-dose liquid bottles (for children or recurring infections) or as 1-gram single-dose oral packets.

Administration: Shake the mixed liquid well before measuring your dose. You can take it with or without food, though taking it with a meal can help reduce stomach upset. Do not take antacids that contain aluminum or magnesium within two hours of your dose.

Storage: Store the reconstituted liquid at room temperature and discard any unused portion after 10 days.

Preparation: The dry powder must be reconstituted with water by your pharmacist before use

Gastrointestinal reactions: The most common are diarrhea, nausea, abdominal pain, and vomiting (with a lower incidence than erythromycin).
Cardiovascular risk: May prolong the QT interval, increase the risk of arrhythmia (such as apical torsion ventricular tachycardia), especially when combined with other QT prolonging drugs.
Hepatotoxicity: Occasional elevation of transaminase and cholestatic jaundice.
Allergic reactions: rash, angioneurotic edema, rare in severe cases.
Other: Headache, tinnitus, temporary hearing loss (during high-dose or long-term use).

Important Safety Information

Complete Treatment: Always finish your full prescription, even if you start to feel better. Stopping early can allow the infection to return or cause bacteria to become resistant to antibiotics.

Allergies & Reactions: Seek immediate medical help if you experience signs of a severe allergic reaction (like rash, hives, or difficulty breathing) or severe skin blistering and peeling.

Other Nootropics Raw Material Also Available

Delivery Time:Around 3-5 workdays after your payment.

Package:1kg/aluminium foil bag;25Kgs in fiber-drums with two-plastic bags inside

Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum

Drum Size & Volume:I.D.42cm × H52cm,0.08 m³/Drum

Storage:Stored in dry and cool place,keep away from strong light and heat.

Shelf Life:Two years when properly stored.

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