What does Alpha-Arbutin Powder do?

Alpha-Arbutin is scientific name 4-Hydroquinone-α-D-glucopyranoside. It is composed of hydroquinone (hydroquinone) and glucose through α-glycosidic bonds, making it more stable and less likely to be decomposed by skin enzymes.

A small amount is found in natural bear fruit (Bearberry), pear leaves, and wheat germ, but the extraction rate is extremely low (<0.1%) and cannot be satisfied with the market.

In order to meet market demand, Alpha-Arbutin is synthesized by biological enzyme method, with a purity of ≥99% by HPLC.

1.Inhibiting tyrosinase activity

It can directly compete to bind tyrosinase active sites to block the conversion of tyrosine to dopaquinone, which is also a key step in melanin synthesis. It also inhibits melanin, transfer from melanocytes to keratinocytes, and reduces epidermal pigmentation.

It commonly used in daily skin care to solve pigmentation problems. For sun spots/age spots, the area of tan spots can be reduced and the brightness can be improved.

2.Optimize skin tone

Inhibits yellowing and brightens dullness caused by saccharification. At the same time, it can reduce local chromatic aberration, improve skin light transmission, and achieve the effect of even skin tone. It is suitable for staying up late frequently, which causes yellow and dull skin.

3.Low irritation

Because the structure of alpha arbutin is stable, it is not easy to be interpreted by skin enzymes to release hydroquinone. Therefore, it is low in irritation, which shows that it is gentle and can be used for sensitive skin and patients with acne, without risk of peeling, redness and swelling, and is safer.

4.Prepayment anti-black

Scavenge UV-induced reactive oxygen species (ROS) and block inflammatory factor signaling. Commonly used in medical repair dressings and postoperative soothing creams. Using Alpha-Arbutin products containing Alpha-Arbutin in the medical beauty process can shorten the erythema period by 2 days and reduce the incidence of pigmentation after photoelectric surgery.

The formula for enhancing efficiency can be achieved. Alpha arbutin is often combined with the following products. It is mainly used in the cosmetics industry and is often used by high-end brands and cosmetics brands' skin care products.

1) α-arbutin (additional amount 2%) + nicotinamide (additional amount 5%) + chitosamine (additional amount 1%). This formula can inhibit melanin synthesis, block melanin transfer, and accelerate metabolism

2) The amount of α-arbutin is added 1% and combined with bosein (additional amount 3%) + ergothionein (additional amount 0.5%) to achieve brightening, promote collagen synthesis, and combine three antioxidant effects.

These products mentioned at the same time can be provided by Xi'an Tongze Bio, and are all high-purity raw materials. Welcome to consult.

Alpha-Arbutin is one of the most mild and effective whitening ingredients at present, and its side effects are extremely low. You only need to pay attention to the following points.

1. Product selection

Identify α-arbutin (non-β type), check the COA report, confirm the α configuration formula, and the product purity is >99%. Avoid formulas containing ethanol and high concentrations of flavors to reduce the superposition of irritation.

2. Standardized use

In daily skin care, when used for the whole face, you can choose to add Alpha-Arbutin≤2%. For local fading, Alpha-Arbutin is required to be added to ≤3%.

The number of times used is only 1-2 times a day. It can be used in the morning and evening, and it is more effective at night. It needs to be paired with sunscreen (SPF30+) when used during the day.

3. Risk combination

Alpha-Arbutin cannot be combined with 20% fruit acid, high concentration of copper peptide, and strong oxidizing agents (such as benzoyl peroxide).

1.Sugimoto, K., et al. (2005). "Inhibitory effects of α-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model." Biological and Pharmaceutical Bulletin, 28(3), 460-464.

2.Funayama, M., et al. (1995). "Effects of α- and β-arbutin on activity of tyrosinases from mushroom and mouse melanoma." Journal of Bioscience and Bioengineering, 79(4), 363-365.

3.Boissy, R. E., et al. (2005). "The effect of α-arbutin on melanogenesis: in vitro and clinical studies." Journal of Dermatological Science, 40(2), 136-142.

4.Kim, Y. M., et al. (2016). "Alpha-arbutin reduces post-inflammatory hyperpigmentation after Q-switched Nd:YAG laser treatment." Dermatologic Therapy, 29(1), 24-29.

5.Hakozaki, T., et al. (2002). "The effect of niacinamide on reducing cutaneous pigmentation." British Journal of Dermatology, 147(1), 20-31.