| Product Name | Desmopressin Acetate |
| Another name | DDAVP,Minirin |
| Appearance | White or almost white crystalline powder |
| Assay | 99% by HPLC |
| Molecular Formula | C₄₆H₆₄N₁₄O₁₂S₂ • C₂H₄O₂ |
| CAS Number | 16789-98-3/62357-86-2 |
| Solubility | Exhibits excellent solubility in both water and dimethyl sulfoxide (DMSO), but slightly less solubility or suspension in ethanol (Ethanol), depending on supplier's testing standards |
| Storage | In order to ensure its stability, it is usually recommended to store it in a cool, dry place and avoid light. Some high-purity standards need to be stored at low temperature (such as -20°C). |
Products Description
What is Desmopressin Acetate?
Desmopressin acetate is a synthetic octapeptide hormone that is an analog of the body's natural arginine vasopressin (antidiuretic hormone). It is also known as DDAVP or 1-desamino-8-D arginine vasopressin.
Desmopressin acetate is a highly efficient and safe synthetic hormone that precisely regulates water reabsorption in the kidneys, providing a core treatment option for patients with diabetes insipidus, nocturia and specific bleeding disorders. But the key to the success of its use lies in strict compliance with water restrictions to avoid serious side effects.
There are only two differences in the chemical structure of desmopressin acetate and natural antidiuretic hormone. These two changes are the key to its longer lasting effect and fewer side effects.
Xi 'an Tongze can provide other API products, the catalog is as follows, welcome to consult!
| Name | CAS No. | Purity |
| Sunifiram | 314728-85-3 | 99.00% |
| Unifiram | 272786-64-8 | 99.00% |
| Idebenone | 58186-27-9 | 99.00% |
| Pramiracetam | 68497-62-1 | 99.00% |
| Fasoracetam | 110958-19-5 | 99.00% |
| Oxiracetam | 62613-82-5 | 99.00% |
| Galantamine Hydrobromide | 69353-21-5 | 98.00% |
| Tianeptine | 66981-73-5 | 99.00% |
| Tianeptine sodium | 30123-17-2 | 99.00% |
| Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.00% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) | 2521-07-5 | 99.00% |
| Agomelatine | 138112-76-2 | 99.00% |
| 6-Paradol 98% | 27113-22-0 | 98% Oil form |
| 6-Paradol 50% | 27113-22-0 | 50% Powder form |
| Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.00% |
| Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.00% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.00% |
| Noopept,GVS-111 | 157115-85-0 | 99.00% |
| Coluracetam | 135463-81-9 | 99.00% |
| N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.00% |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
| Citicoline | 987-78-0 | 99.00% |
| PRL-8-53 | 51352-87-5 | 98.00% |
| NSI-189 Phosphate | 1270138-41-4 | 99.00% |
Application of Desmopressin Acetate powder
Desmopressin acetate is a synthetic analogue of the natural antidiuretic hormone (ADH, also known as arginine vasopressin). Its primary action is to increase water reabsorption in the renal collecting ducts by selectively activating V2 receptors, thereby concentrating urine and reducing urine output. It is available in multiple dosage forms, each suited to different clinical scenarios.
| Clinical Scenario | First-Line Dosage Form(s) | Alternative | Contraindicated/Not Indicated |
|---|---|---|---|
| Central Diabetes Insipidus | Tablet, lyophilisate, solution, nasal spray, injection | - | - |
| Pediatric Nocturnal Enuresis | Tablet, lyophilisate, oral solution | - | Nasal spray |
| Adult Nocturia | Lyophilisate (low-dose, e.g., 25–50 μg) | - | Nasal spray |
| Bleeding Disorders (Hemophilia A, vWD) | IV injection | High-dose nasal spray (off-label) | Oral formulations (unreliable absorption) |
| Diagnostic Tests | Injection, nasal spray | - | - |
Benefits of Desmopressin Acetate powder
1. Central Diabetes Insipidus (CDI)
Desmopressin acetate is highly effective as an antidiuretic replacement therapy for patients with central diabetes insipidus.
2. Primary Nocturnal Enuresis (Bedwetting) in Children
Desmopressin acetate demonstrates statistically significant efficacy in reducing the frequency of wet nights in children aged 5-17 years.
A 2025 randomized controlled trial demonstrated that combining desmopressin acetate with parasacral transcutaneous electrical nerve stimulation (PTENS) for 15 weeks significantly reduced wet nights, with improvement maintained six months after intervention completion (p<0.001)-8.
3. Nocturia in Adults
Desmopressin is effective in reducing nighttime urination frequency and increasing uninterrupted sleep duration.
The use of desmopressin acetate tablets in patients with an established diagnosis results in reduced urinary output with increased urine osmolality, allowing resumption of a more normal lifestyle with decreased urinary frequency and nocturia.
Things to note of Desmopressin Acetate powder
While highly effective, desmopressin is a potent antidiuretic agent that may lead to water intoxication and hyponatremia. In the MS nocturia study, 4 of 17 patients (23.5%) developed asymptomatic or minimally symptomatic hyponatremia, which was dose-related-3.
Warning Signs Requiring Immediate Medical Attention:
Headache, nausea/vomiting
Unexplained weight gain
Decreased serum sodium
Confusion, seizures, or coma (severe cases)-5-6
Strict Fluid Restriction is Required: Patients must avoid drinking from 1 hour before until 8 hours after each dose to prevent hyponatremia
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Name：Alice
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FAQ
Q: Can we offer Related products of Desmopressin Acetate powder?
A: Yes, We can provide other API,welcome to consult.
Q: How do you treat quality complaint ?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:Can customized packaging be carried out of Desmopressin Acetate powder?
A:Of course, it can be repackaged. For instance, it is commonly used in vials or freeze-dried powder bottles for beauty purposes. We can provide them all.
Q:Is there a discount?
A:Of course, welcome to contact us. Price would be different based on different quantity. For bulk quantity, we will have discount for you.At the same time, we have a detailed list of discounted products and products with large inventory every quarter.
Q:Whether customized services can be provided
A:We offer ODM/OEM services and can manufacture according to specified formulations. We have our own designers who can design and customize private brands, packaging. Our customized service from the production of raw materials, design of brands/packaging, to the production of customized packaging, and then to packaging, mailing packages, one-stop production line, welcome to visit.
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