| Product Name | Paraxanthine |
| Synonym | 1,7‑Dimethylxanthine |
| IUPAC Name | 1,7‑dimethyl‑3H‑purine‑2,6‑dione |
| CAS No. | 611‑59‑6 |
| Appearance | White to off‑white crystalline powder |
| Molecular Formula | C₇H₈N₄O₂ |
| Molecular Weight | 180.16 g/mol |
| Purity | ≥98% HPLC |
| Package | Cold‑pack / ice‑pack transportation, light‑proof required |
| Storage | Sealed, cool and dry place, ‑20 °C recommended for long‑term storage |
| Shelf-Life | 24Months |
Products Description
What Is Paraxanthine 1,7‑Dimethylxanthine?
Paraxanthine, also named 1,7‑Dimethylxanthine (CAS: 611‑59‑6), belongs to the methylxanthine alkaloid family, same chemical class as caffeine, theophylline and theobromine. It is the major human metabolite of caffeine generated by liver CYP1A2 enzyme metabolism. This compound appears as off‑white to white crystalline powder. It is widely used for pre‑clinical lab research, biomarker study, and formulation development of dietary supplement raw materials. For Research Use Only. Not intended for human direct‑use or therapeutic applications.
Applications OF Paraxanthine
1.Biomedical & Laboratory Research Caffeine‑metabolism biomarker research, pre‑clinical pharmacology assays, in‑vitro and animal model studies of methylxanthine compoundsPMC.
2.Analytical Reference Standard Used for HPLC, UV‑spectroscopy method development & validation; quantitative testing of biological samples for caffeine metabolic pathways.
3.Dietary Supplement R&D & Formulation Prototyping Raw‑material screening for sports‑nutrition, cognitive‑focus and energy‑support formula development. For lab‑scale formula trial only; commercial launch requires full local regulatory review and approval.
4.Chemical‑pharmacology Compound Library Methylxanthine compound library building for new‑compound screening and structure‑activity relationship research.
Compound Properties & Research‑Observed Benefits
1.Distinct pharmacological mechanism Acts as adenosine receptor antagonist; selectively inhibits PDE9 enzyme to modulate NO‑cGMP signaling, a pathway not targeted by caffeinePMC.
2.Favorable pharmacokinetic profile in research data Shorter half‑life than caffeine in pharmacology tests, which reduces cumulative exposure risk in experimental settings.
3.Pre‑clinical central nervous system activity Exhibits locomotor‑activating effects in animal model studies, widely investigated for cognition‑related mechanism research.
4.Research reference compound for methylxanthine comparison Well‑characterized molecule for side‑by‑side profiling against caffeine, theophylline and theobromine in formulation R&D projects.
Paraxanthine vs Similar Methylxanthine Compounds
Disclaimer: All advantages described refer to pre‑clinical research characteristics and raw material R&D properties only. Not for human medical claims or therapeutic use.
Compared with other classic methylxanthine compounds including Caffeine, Theophylline and Theobromine, Paraxanthine (1,7‑Dimethylxanthine) displays unique pharmacological profiles, safer research performance and higher R&D value for cognitive and energy‑related mechanism studies, making it a more targeted compound for advanced laboratory research and new formulation prototyping.
1. Higher Target Selectivity (Unique PDE9 Inhibition)
Unlike Caffeine, which non‑specifically affects multiple enzyme and receptor pathways, Paraxanthine shows selective PDE9 inhibitory activity. This unique mechanism allows researchers to study cGMP/NO signaling pathways independently, providing more accurate experimental data for neural and cognitive mechanism research.
2. Shorter Half-Life & Lower Accumulation Risk
In pharmacokinetic studies, Paraxanthine possesses a shorter half-life than Caffeine. It effectively avoids long-term compound accumulation in experimental models, offering better controllability for in vivo trials and repeated-dose research.
3. Mild & Stable Biological Response
Compared with Theophylline (which causes strong cardiac and respiratory stimulation in research models) and high-dose Caffeine toxicity interference, Paraxanthine exhibits milder, more stable physiological responses in pre-clinical assays. It reduces experimental background noise and improves data repeatability.
4. Cleaner Metabolic Background
As the major downstream metabolite of Caffeine, Paraxanthine does not produce complex secondary metabolites during research testing. It serves as a purer reference compound for caffeine metabolism pathway analysis, biomarker detection and clinical sample calibration.
5. Great Potential for Precision Formulation R&D
Different from Theobromine (mainly cardiovascular and metabolic research), Paraxanthine is more targeted for cognition-support, neural regulation and energy metabolism research. It has become a popular raw material for next-generation precision dietary supplement prototype development.
6. High Purity & Batch Stability for Lab Use
Our Paraxanthine powder features low impurity content, stable batch difference and consistent HPLC profile. Compared with crude plant-extracted xanthine mixtures, the monomer product ensures highly reliable and reproducible experimental results.
Shipping & Delivery
Shipping Condition: Room‑temperature shipment for solid powder; ice‑pack cold shipping optional on request
Order Processing: In‑stock items ship within 1‑3 working days after order confirmation
Transport Options
International Express(DHL/FedEx/UPS): For sample & small‑batch orders, transit 3‑7 working days
Air Freight: For medium‑bulk quantity, transit 7‑12 working days
Sea Freight: For large‑volume bulk orders, transit 20‑35 working days
Shipping Documents Provided: COA, SDS‑MSDS, Packing List, Commercial Invoice
Custom Notice: Recipient takes responsibility for local import tax, duty and customs compliance; please verify local import regulations before placing order
Packing Protection: Vacuum aluminum foil inner bag with desiccant, anti‑moisture packaging for overseas transit

Customer Feedback

CONTACT PAGE
We provide bulk & sample Paraxanthine powder for R&D purpose. Contact us at my information to get quote and technical documents.
1.Inquiry methods:
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information:
Name:Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
FAQ
Q:What is your standard purity for Paraxanthine?
A: Our standard purity ≥98 %, tested by HPLC‑UV. Custom purity requirements are available upon request.
Q: What is the solubility of Paraxanthine?
A: Slightly soluble in water; soluble in DMSO, sparingly soluble in ethanol. Sonication is recommended to prepare stock solutions.
Q: What storage conditions are required?
A: Store sealed in cool‑dry environment. Long‑term storage recommended at ‑20 °C. Unopened shelf‑life is 2 years.
Q: What documents can you provide for Paraxanthine?
A: COA, SDS‑MSDS, HPLC chromatogram are available. NMR spectrum can be provided on customer request.
Q: What pack sizes do you offer?
A:Sample sizes:1 g‑10 g vacuum aluminium foil bag; bulk size:25 kg fiber drum. Custom packaging is supported.
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