Product name	J147
CAS NO.	1146963-51-0
Category	Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity	99%
Appearance	White powder
Shelf life	2 years
Usage	J147 is an Neurotrophic compound.
Storage	J147 should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

J-147 Powder

Product Name	J-147 Powder
Chemical Formula	C18H17F3N2O2	Molecular Weight	350.34
CAS	1146963-51-0	Batch Quantity	400KG
Batch No.	MLP-PPH-20231114	Manufacture Date	2025.11.14
Report Date	2025.11.17	Retest Date	2027.11.13

Testing Items		Specifications	Test Results
BP2010 /EP6	Appearance	crystalline powder	Conforms
	Melting point	About 205°C	206.4°C~206.7°C
	Identification	Meet the requirements	Conforms
	Appearance of solution	Clear, not more intense than Y7	Conforms
	PH	2.4~3.0	2.60
	Loss on drying	≤0.5%	0.04%
	Sulphated ash	≤0.1%	0.01%
	Heavy metals	≤20 ppm	<20 ppm
	Related substances	≤0.25%	Conforms
	Assay	99.0%~101.0%	99.8%
USP32	Identification	Meet the requirements	Conforms
	Loss on drying	≤0.5%	0.04%
	Residue on ignition	≤0.1%	0.01%
	Heavy metals	≤0.003%	<0.003%
	Residue solvent - Ethanol	≤0.5%	<0.04%
	Chloride	16.9%~17.6%	17.1%
	Assay	98.0%~102.0%	100.0%
Conclusion: The product complies with BP2010/USP32/EP6 standard

Cognitive Enhancement: Restores memory and learning capabilities in aged animal models

Neuroprotection: Shields neurons from amyloid-beta toxicity and oxidative stress

Mitochondrial Support: Boosts cellular energy production in brain cells

Anti-Aging Properties: Reverses age-related epigenetic changes in the hippocampus

Therapeutic Development: Validated platform for Alzheimer's disease drug discovery

Backed by peer-reviewed research:

Oral Bioavailability: 30% bioavailability in rodent models

Effective Dosing: 30-100 mg/kg daily oral administration in preclinical studies

Cognitive Improvement: 2-3x enhancement in spatial memory tasks in aged mice

Mechanism of Action: Activates neurotrophic factors and reduces neuroinflammation

Long-Term Safety: Well-tolerated in chronic administration studies

Alzheimer's Disease Studies: Ideal for investigating amyloid-beta clearance mechanisms

Cognitive Neuroscience: Enhances memory formation and synaptic plasticity research

Aging Research: Validated tool for studying brain aging and age-related cognitive decline

Drug Discovery: High-throughput compatible for identifying novel neuroprotective compounds

Mitochondrial Biology: Investigates cellular energy metabolism in neurodegeneration

Comprehensive analytical testing: HPLC, NMR, Mass Spectrometry

Endotoxin testing for cell culture applications

Sterile filtering available upon request

Full documentation provided with every order, including COA

10 mg research vial

50 mg laboratory pack

100 mg bulk research quantity

1 kg industrial research package

Custom quantities available for collaborative projects

Based on published research and supplier data, the following dosages are used in preclinical studies:

Oral administration in mice: 200 ppm in diet (equivalent to approximately 30-50 mg/kg body weight daily)

Duration of treatment: 6 months in aging studies showing cognitive improvement

In vitro studies: Effective concentration range of 1-10 μM (0.35-3.5 μg/mL in solution)

Recommended solvent: DMSO (soluble up to 100 mM) or ethanol (soluble up to 100 mM)

Dilution advice: For in vivo studies, further dilute in physiological saline or water before administration

Storage of solutions: Prepared solutions can be stored at -20°C for up to 3 months

Species differences: Dosages may vary significantly between different animal models

Study-specific adjustments: Researchers often adjust dosages based on specific experimental endpoints

Route of administration: Oral administration is most common, but intravenous and intraperitoneal routes have also been used in research

Purity impact: Dosage calculations should be based on 99% purity standard

Peer-Recognized: Cited in over 50 leading neuroscience publications

Reproducible Results: Consistent biological activity across all batches

Technical Support: Access to our team of neuroscience researchers

Global Shipping: Worldwide delivery with proper documentation

Manufacturer Direct: Sourced directly from GMP-compliant facilities

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Delivery Time:Around 3-5 workdays after your payment.

Package:1kg/aluminium foil bag;25Kgs in fiber-drums with two-plastic bags inside

Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum

Drum Size & Volume:I.D.42cm × H52cm,0.08 m³/Drum

Storage:Stored in dry and cool place,keep away from strong light and heat.

Shelf Life:Two years when properly stored.

Package	1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
Transit	Fedex, TNT,DHL,EMS,and so on.
Shipping port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	1-2 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

Q: 1. I want to know more details about the product, how can I contact you?

A: You can send us an email inquiry at any time. For more accurate quotes, I need the following information: product name, order quantity, receipt country, quality requirements, etc.

Q: 2. How do I know if your products are real or fake?

A: We will inspect every shipment. I can provide test reports including HPLC, MS and HNMR if you want. Please find a professional chemist to help you confirm the authenticity of the test report.
Of course, you can also purchase samples to take you around your trust.

Q: 3. How do you ensure the safety of the package I receive?

A: I want to receive the package safely, I first need to know your delivery address, do you have a preferred courier method, did you buy it from China?
Why do you want to know?
Because each country has different requirements for imported packages, especially chemical products, you need to know the basic information to provide you with the safest choice.
At present, we have professional customs clearance agents in EU countries, the United States, the United States, Canada, and Southeast Asia. We have professional customs clearance agents to ensure the safety of packages.

Q: 4. How to pay?

A: Our payment channels include bittoin, bank card, Western Union, Allegitudes, etc.
It is usually recommended that customers pay with Bitcoin, because the fee is low, the entry speed is fast, and the security is guaranteed.

Q: 5. How long does it take to receive the package?

A: This will vary according to the delivery method you choose. I will briefly introduce our commonly used special lines.
Usually European countries 10-15 days after sending you the tracking number.
In the United States and Canada, it usually takes 7-10 days.
Southeast Asian countries are 3-7 days.

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