| Product Name | Protirelin acetate Peptide |
| Synonyms | Protirelin , Protirelin acetate, Protirelin acetate Peptide |
| Appearance | White to Light Yellow Powder |
| Sequence | {pGlu}-His-Pro-NH₂ |
| Assay | 99% by HPLC |
| Molecular Formula | C16H22N6O4(freebase),C38H56N12O14(acetate) |
| CAS Number | 120876-23-5/24305-27-9 |
| Solubility | H2O/DMSO(Ultrasound-assisted dissolution) |
| Storage | Cool dry place( Store at -20°C, away from the light) |
Products Description
What is Protirelin acetate Peptide?
Protirelin Acetate is an acetate form of thyroid stimulating hormone-releasing hormone. In biochemistry and medicine it is better known as TRH.
From the chemical structure, it is a tripeptide, namely pyroglutamyl-histidyl-prolylamide (pGlu-His-Pro-NH2). In clinical diagnosis, it has been used as a standard reagent for the "TRH stimulation test" to evaluate the function of the thyroid and hypothalamic-pituitary axis.
Xi 'an Tongze can provide other peptide products, the catalog is as follows, welcome to consult!
|
Product Name |
CAS No. |
|
Goralatide |
127103-11-1/120081-14-3 |
|
ARA-290(Cibinetide) |
1208243-50-8 |
|
N-acetyl Semax Amidate |
2920938-90-3 |
|
N-AC-selank-amidate |
N/A |
|
Aviptadil Acetate |
40077-57-4 |
|
GLP-1(1-37) |
87805-34-3 |
|
GIP (huMan) |
100040-31-1 |
|
N-Acetyl-Semax |
N/A |
|
N-Acetyl Selank |
N/A |
|
S-Phenylacetyl Larazotide |
N/A |
|
Dermorphin |
77614-16-5 |
|
PEG-MGF |
N/A |
|
Met-enkephalin |
58569-55-4 |
|
Pramlintide Acetate |
196078-30-5 |
|
Dalargin |
81733-79-1 |
|
Abaloparatide |
247062-33-5 |
|
N-Acetyl Larazotide |
N/A |
|
Humanin |
330936-69-1 |
|
Adamax |
N/A |
COA of VIP Peptide
|
Product Name |
Protirelin acetate Peptide |
CAS Number |
120876-23-5 |
|
Manufacture Date |
2026/03/28 |
Expiration Date |
2028/02/27 |
|
Batch Number |
TZ20260328 |
Batch Quantity |
1KG |
|
Sequence |
{pGlu}-His-Pro-NH₂ | ||
|
Item |
Specification |
Results |
|
Appearance |
White to Light Yellow Powder |
White powder |
|
Purity (By HPLC) |
≥98.0% |
99.10% |
|
Acetic acid Content (HPL.C) |
≤15.0% |
7.30% |
|
Water Content |
≤8.0% |
3.49% |
|
Related Solvents(GC)
|
Acetonitrile≤410ppm |
10ppm |
|
Methanol ≤3000ppm |
110ppm |
|
|
Methylene chloride≤600ppm |
Not detected |
|
|
lsopropyl ether ≤5000ppm |
Not detected |
|
|
N,N.Dimethylformamide≤880ppm |
Not detected |
|
|
Peptide Content |
Reported value |
90.12% |
|
Bacterial Endotoxins |
DCM≤5EU/mg |
<5EU/mg |
|
Conclusion |
the product conforms with enterprise standard and qualified |
|
|
Storage |
Keep in dark and cool dry place -20 to 8°C |
|
|
Shelf life |
2 Years When Stored properly |
|
Application of Protirelin acetate Peptide
1.Core clinical application: Diagnosis of thyroid and pituitary function
| Application scenarios | Specific instructions |
| Differential diagnosis of hypothyroidism | Help distinguish "primary" hypothyroidism (the lesion is in the thyroid itself) and "secondary" hypothyroidism (the lesion is in the pituitary gland or hypothalamus), and guide subsequent treatment plans -4-9. |
| Assisted diagnosis of Graves' disease | Assists in the diagnosis of autoimmune thyroid diseases, such as Graves' disease-4-9. |
| Assessing pituitary reserve function | Used to determine whether the reserve capacity of the pituitary gland to secrete thyroid-stimulating hormone (TSH) is normal -4-9. |
2.In addition to clinical diagnosis, Protirelin, as a highly conserved neuropeptide, is also an important tool in neuroscience research.
| Research Interests | Research contents |
| Thermoregulation research | In animal experiments, Protirelin has been proven to cause a dose-dependent, temporary increase in body temperature and is used to study the hypothalamic regulation mechanism of body temperature-6-8. |
| neuromodulation and development | As a study on the role of neuropeptides in regulating central nervous system functions such as feeding, arousal, and antidepressant-3-6-8. |
Precautions
Regulatory Restrictions: In its clinical and commercial description, Protirelin Acetate is intended for research use only and not for direct therapeutic use.
People who should use it with caution: There are strict contraindications for clinical use. Women with cardiac insufficiency, bronchial asthma, severe pituitary insufficiency, pregnant women and lactating women should use it with caution.
Drug interference: Before the test, growth hormone, contraceptive pills and other drugs that may interfere with the results need to be stopped.
Important prerequisites and risks for use:
1.Adverse reactions are common but mild: about 50% of patients will experience some transient adverse reactions after injection, but they usually subside within a few minutes. The most common ones are: facial flushing, nausea, urgency to urinate, dizziness, and bad taste in the mouth.
2.Serious but rare risks: In rare cases (especially in patients with pre-existing pituitary macroadenoma), the injection may induce a pituitary apoplexy (pituitary hemorrhage or infarction), which can manifest as a sudden, severe headache, visual disturbance, etc., which is a medical emergency
The core benefit of Protirelin Acetate is that it serves as a "functional probe of endocrine function" and has irreplaceable value in the diagnosis of hypothalamic-pituitary-thyroid axis-related diseases. Although early studies also explored its therapeutic potential in the neuropsychiatric field, this is still within the scope of scientific research and is not its approved indication.
Packing & Shipping
Customer Feedback
FAQ
Q: Can we offer Related products of Protirelin Acetate Peptide?
A: Yes, We can provide other peptides,welcome to consult.
Q: What is the shelf life of Protirelin Acetate lyophilized powder ?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:Can Protirelin Acetate be used in neurological research?
A:Yes, beyond its endocrine applications, Protirelin Acetate is widely studied for its neuroprotective effects and its role in treating consciousness disorders following brain injury.
Q:Is there a discount?
A:Of course, welcome to contact us. Price would be different based on different quantity. For bulk quantity, we will have discount for you.At the same time, we have a detailed list of discounted products and products with large inventory every quarter.
Q:Whether customized services can be provided
A:We offer ODM/OEM services and can manufacture according to specified formulations. We have our own designers who can design and customize private brands, packaging. Our customized service from the production of raw materials, design of brands/packaging, to the production of customized packaging, and then to packaging, mailing packages, one-stop production line, welcome to visit.
CONTACT PAGE
1.Inquiry methods：
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information：
Name：Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
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