Products Description
What is Nano-Hydroxyapatite?
Nano-Hydroxyapatite (n-HAp) is a synthetic biomimetic calcium phosphate material, chemically identical to the inorganic mineral component of human enamel and bone tissue. Thanks to its nanoscale particle size, it provides much higher specific surface area and bioactivity than conventional micron hydroxyapatite. It is highly biocompatible, osteoconductive and non-cytotoxic. Our nano-hydroxyapatite is produced by controlled hydrothermal synthesis, with tunable particle size, narrow particle distribution and stable Ca/P ratio. We supply multiple grades: cosmetic grade for oral care, medical grade for bone/dental device, food grade for calcium supplement and research grade for university lab study. It is widely used in remineralizing toothpaste, dental varnish, bone graft scaffold, implant coating, skincare and biomaterial R&D. We provide sample testing service and full characterization reports for registration and audit.
Similar Biomaterial APIs
Beta-Tricalcium Phosphate (β-TCP)
Calcium Phosphate Dibasic
Hydroxyapatite micro powder
Bioactive Glass Powder
Calcium Carbonate
How to Choose Nano-Hydroxyapatite
When selecting nano‑hydroxyapatite (n‑HAp), the most critical step is to match the model, morphology, particle size and purity to your end application. We have categorized our full HAP series into Type 1 (conventional hydrothermal HAp) and Type 2 (calcined at 800°C HAp) for different manufacturing scenarios. Below is our application-based selection guide with our standard model list.
Our HAP Model Specification Reference
| Model | Code | Morphology | Grain Size & Purity | Recommended Application |
| HAP01 | 01-2u | spheroid | 2μm, 96% | Toothpaste, soil treatment, mouthwash |
| HAP01 | 01-200 | acicular | 200nm,95% | Toothpaste, soil treatment, mouthwash |
| HAP01 | 01-60 | acicular | 60nm,96% | Toothpaste, soil treatment, mouthwash |
| HAP02 | 02-40 | acicular | 40nm,96% | Protein separation, chromatography |
| HAP03 | 03-20 | acicular | 20nm,97.5% | Low purity artificial bone, bone scaffold |
| HAP04 | 04-20 | acicular | 20nm,99% | High purity artificial bone, bone peg |
| HAP05 | 05-20 | rod-like | 20nm,99% | High purity artificial bone, bone peg |
| HAP06 | 06-80 | spheroid | 80μm,96% | Soil remediation |
| HAP07 (Type2, 800℃ calcined) | 07-15u | spheroid | 15μm (≤30μm) | 3D Printing, thermal spraying |
| HAP07 | 07-50u | spheroid | 50μm (30–80μm) | Artificial bone coating, thermal spraying |
| HAP07 | 07-100 | spheroid | 100μm (≥80μm) | 3D Printing, thermal spraying |
| HAP07 | 07-200 | spheroid | 200μm | 3D Printing, bone repair |
| HAP07 | 07-3h | spheroid | 3mm | Bone repair, bone filling |
Core technical checkpoints before bulk order
1.Morphology: acicular / rod-like for high bioactivity; spheroid for good flowability, thermal spraying and 3D printing
2.Purity: 99% high purity for medical implant; 95%~97.5% for oral care and soil application
3.Calcination status: Type 2 (800°C calcined) has higher thermal stability, cannot be used for oral remineralization
4.Supporting documents: COA, XRD, PSD, heavy metal test, microbial report
5.Compatibility trial: We strongly suggest lab formulation test before bulk wholesale shipment
Applications of Nano-Hydroxyapatite powder
1.Oral care formulations: remineralizing toothpaste, dental varnish, mouthwash, dental polishing paste, fluoride-free enamel repair products
2.Dental & orthopedic medical devices: bone graft filler, 3D printing bone scaffold, implant surface coating, periodontal repair material
3.Cosmetic raw material: gentle polishing agent, skin repair additive, biomimetic filler for cosmetic formulations
4.Food & nutraceutical: calcium fortification raw material for dietary supplements
5.Pharmaceutical carrier: drug delivery carrier for sustained-release formulation research
6.Academic & industrial R&D: tissue engineering, biomaterial composite, ceramic material development
Safety Warning
1.The powder may cause irritation to eyes and respiratory tract when inhaled. Wear dust mask, goggles and gloves during handling.
2.Nanoparticle dust control is required in clean workshop. Avoid long-term dust exposure.
3.Medical grade n-HAp is only for medical device manufacturing; finished medical products need local device registration.
4.Not for direct injection without validated medical device formulation.
5.Store sealed and dry, nano powder tends to absorb moisture and agglomerate under high humidity.
FAQ
Q: Does the powder agglomerate, and how is it dispersed for formulation?
A: Our advanced drying and surface-modification techniques prevent hard agglomeration. The powder exhibits excellent redispersibility in aqueous systems, making it highly compatible with standard slurry preparations, cosmetic emulsions, and hydrogels.
Q: How can I request sample kits, technical data sheets (TDS), or a commercial quotation?
A:Qualified R&D scientists, product formulators, and procurement managers can submit an inquiry via our corporate portal or click below to connect directly with our biomaterials technical support team.
Q: What packaging materials are used to ensure product integrity and prevent moisture uptake?
A: To prevent moisture absorption and preserve nano-scale integrity during global transit, our n-HAp is double-packaged in medical-grade polyethylene (PE) bags, vacuum-sealed within aluminum foil bags, and secured in a sturdy fiber drum.
Q: Is your Nano-Hydroxyapatite certified for cosmetic, oral care, or medical device applications?
A: Yes. We supply distinct grades tailored to specific industries: Cosmetic Grade (for toothpastes, mouthwashes, and enamel repair gels) and Medical/Biomaterial Grade (for bone graft substitutes, scaffold coatings, and implants), backed by comprehensive ISO and biocompatibility testing reports.
Q: Is nano-hydroxyapatite safe for toothpaste?
A:Cosmetic grade n-HAp complies with EU SCCS and cosmetic raw material requirements, widely used in fluoride-free remineralization toothpaste.
CONTACT PAGE
We are direct manufacturer of Nano-Hydroxyapatite n-HAp CAS 1306-06-5. Send us your required grade, target particle size, application and target market regulation. We will prepare formal quotation plus COA and full characterization files for your formulation trial and registration.
1.Inquiry methods：
Email:alice@xaheshun.com
Whatspp:+8618509260106
Online instant messaging
2.Contact Information：
Name：Alice
Telephone :+8618509260106
Email:alice@xaheshun.com
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