Chemical & Physical Specifications
|
Product Name |
4'-Methoxyacetophenone (Acetanisole / p-Acetylanisole) |
|
CAS Number |
100-06-1 |
|
EC / EINECS Number |
202-815-9 |
|
Molecular Formula |
C9H10O2 (CH3OC6H4COCH3) |
|
Molecular Weight |
150.17 g/mol |
|
MDL Number |
MFCD00008745 |
|
Appearance |
White to off-white crystalline solid; colorless to pale yellow liquid when molten |
|
Odor |
Sweet, warm, floral-balsamic, vanilla / almond / hawthorn-like |
|
Purity (Assay, GC) |
≥ 99.0% (FCC / industrial grade available) |
|
Melting Point |
38 – 39 °C |
|
Boiling Point |
About 258 °C |
|
Density (25 °C) |
About 1.08 g/cm³ |
|
Refractive Index (n20/D) |
About 1.554 |
|
Solubility |
Insoluble in water; miscible with ethanol, ether, acetone and fixed oils |
|
Flash Point |
About 110 °C (closed cup) |
|
Acidity / Residue on Ignition |
Comply with FCC / enterprise standard |
|
Storage |
Keep tightly sealed, in a cool, dry, ventilated warehouse, away from heat and light |

Products Description
4'-Methoxyacetophenone (Acetanisole) - Bulk Fragrance & Flavor Chemical
4'-Methoxyacetophenone - also known as Acetanisole, p-Acetylanisole or 4-Acetoanisole - is an aromatic ketone that occurs naturally in anise seed and has a characteristic sweet, floral, warm odor reminiscent of vanilla, almond and hawthorn blossom. It is a white to off-white crystalline solid (melting point ~38–39 °C) that liquefies to a colorless to pale yellow oily liquid on gentle warming.
Because of its pleasant warm-balsamic, nutty-vanilla note and good stability in soap and cosmetic bases, 4'-Methoxyacetophenone is widely used as a fragrance and flavoring compound. It is listed by FEMA (No. 2005) and is GRAS under FDA 21 CFR 172.515 for use as a flavoring agent. In addition, it serves as a valuable organic intermediate in pharmaceutical synthesis, resin/coating chemistry and photochemical research.
We supply industrial and FCC/Flavor-grade 4'-Methoxyacetophenone in drums and IBCs, with full COA, MSDS/SDS and technical documentation for B2B buyers, flavor houses, fragrance manufacturers and formulators worldwide.
COA
Certificate Of Analysis
|
Product Name |
4'-Methoxyacetophenone Powder |
Batch No. |
HZP20261102 |
|
|
Quantity |
401.5KG |
Man. Date |
2026-11-03 |
|
|
Packaging |
25KG/Drum |
Test Date |
2026-11-04 |
|
|
Expiry Date |
2028-11-04 |
Report Date |
2026-11-04 |
|
|
Test Items |
Standard |
Test Results |
||
|
Characteristics |
White or practically white crystalline powder, Is odorless and has a bitter taste |
Complies |
||
|
Identification |
Complies |
Complies |
||
|
Solubility |
Freely soluble in water,practically insoluble in alcohol,in chloroform,and in ether |
Complies |
||
|
Melting point |
238~242℃ |
241.5℃ |
||
|
PH |
3.5~5.5 |
4.2 |
||
|
Loss on drying |
≤2.0% |
0.3% |
||
|
Related substances |
Total impuritites≤2.0% |
Complies |
||
|
Residual solvent |
Ethanol ≤5000ppm Ethyl acetate≤5000ppm Dichloromethane≤600ppm Isopropanol ≤5000ppm |
2733ppm 32ppm ND ND |
||
|
Assay |
98.0%~102.0% |
101.0% |
||
|
Conclusion |
Complies with USP41 standards. |
|||
Quality Assurance & Compliance
Batch-specific COA with GC assay, appearance/color, odor, melting point, density and refractive index.
SDS / MSDS and TDS supplied with every shipment; Certificate of Origin and import-filing support on request.
Flavor-grade material meets FCC requirements and is recognized as GRAS (FEMA No. 2005; FDA 21 CFR 172.515).
Note: Buyers are responsible for confirming that their intended use (food, cosmetic, pharmaceutical or industrial) complies with local regulations, and for observing permitted use levels and labeling requirements.
Applications 4'-Methoxyacetophenone Powder
4.1 Fragrance & Perfumery
4'-Methoxyacetophenone is used in floral, hawthorn, mimosa, acacia, lilac and oriental fragrance bases to add a warm, sweet, balsamic nuance. It blends well with coumarin, musk, jasmine and citrus notes and is valued in fine fragrance, soap, detergent, cosmetics, candles and air-care products.
4.2 Food & Beverage Flavoring
Recognized as a safe flavoring substance (FEMA 2005; GRAS), it is used in vanilla, nut, berry, caramel and butter-type flavor compositions for ice cream, baked goods, non-alcoholic beverages, candy and confectionery, typically at low ppm use levels.
4.3 Pharmaceutical & Organic Synthesis Intermediate
It is a versatile building block for active pharmaceutical ingredients and fine chemicals, serving as a precursor for reduction, halogenation, oximation and condensation reactions in the synthesis of drug intermediates and related aromatic ketone derivatives.
4.4 Resin, Coating & Photochemical Use
The compound is used in UV-curable resin formulations, photoinitiator research, polymer chemistry and as a reference substrate in catalysis studies (e.g., ruthenium-catalyzed and reduction chemistry).
Packaging, Storage & Shelf Life
Packaging: 25 kg net fiber carton drums; 200 kg net galvanized/steel drums; custom labeling and neutral packaging available.
Storage: Keep container tightly closed in a cool, dry, well-ventilated area, away from direct sunlight, heat sources and strong oxidizers.
Shelf life: 24 months when stored as directed; retest after opening.
Handling: Avoid inhalation and skin/eye contact; use only with adequate ventilation and standard PPE (see SDS).
Why Choose Our 4'-Methoxyacetophenone
High purity: GC assay ≥ 99.0%, with consistent batch-to-batch odor profile and color.
Flavor/FCC grade available for food and beverage use; industrial grade for synthesis and technical applications.
GRAS status (FEMA No. 2005; FDA 21 CFR 172.515) - suitable for permitted flavor applications.
Good stability and fixation in soap, detergent, cosmetic and candle bases.
GMP/ISO-compliant production with Friedel–Crafts acylation route and controlled distillation/crystallization.
Flexible packaging: 25 kg carton drums, 200 kg steel drums, or IBC/tank for large-volume customers.
Full documentation: batch COA (GC assay, odor, color, density, refractive index), SDS, TDS, Certificate of Origin.
Reliable worldwide logistics by sea, air or express, with customs documentation support.
Storage & Safety Guidance
Storage: Keep container tightly closed, store in cool, dry and dark warehouse, away from strong oxidants and heat source.
Handling: Wear dust mask, safety goggles and chemical resistant gloves. Avoid powder inhalation, skin and eye contact.
First aid: Rinse skin/eyes with plenty of clean water once exposed; seek medical help if irritation continues.
Waste disposal: Dispose residues and packaging according to local pharmaceutical hazardous waste regulations. Refer to SDS for complete hazard statements.
Frequently Asked Questions (FAQ)
Q: What is 4'-Methoxyacetophenone?
A: It is an aromatic ketone, also called acetanisole or p-methoxyacetophenone (CAS 100-06-1), with a sweet, warm vanilla-almond odor, widely used as a fragrance and flavoring agent and as a synthetic intermediate.
Q: Is it food-safe?
A: Yes - the FCC/flavor grade is FEMA No. 2005 and GRAS under FDA 21 CFR 172.515 for use as a flavoring agent. Always use within permitted use levels and local regulations.
Q: What is the MOQ and available packaging?
A: Trial orders start from 25 kg drums; regular supply is 200 kg drums or IBCs/tanks for bulk customers. Contact us for the current price tier.
Q: What purity do you supply?
A: Standard GC purity is ≥ 99.0%. FCC/flavor grade and higher-purity reference grade can be arranged.
Q: Is it soluble in water?
A: No - it is practically insoluble in water but miscible with ethanol, ether, acetone and most fixed oils, which is typical for aromatic ketone fragrances.
Q: What documents do you provide?
A: Batch COA, SDS/MSDS, TDS, commercial invoice, packing list and Certificate of Origin; regulatory dossier support is available on request.
Request a Quote
Looking for a reliable supplier of 4'-Methoxyacetophenone (Acetanisole)? Send us your required quantity, grade (industrial / FCC flavor), destination port and any documentation needs, and our sales team will reply within 24 hours with the latest price, lead time and shipping options.
Product: 4'-Methoxyacetophenone (Acetanisole), CAS 100-06-1, C9H10O2
Grade: Industrial / FCC-Flavor, GC assay ≥ 99.0%
MOQ: From 25 kg drum to 200 kg drum / IBC bulk
Documentation: COA, SDS, TDS, COO included
Name :Serena Pang
Mobile :15667080670
We:15667080670
Whats:+8615667080670
E-mail:Serena@xaheshun.com
Best regards,
Serena Pang
Xi'an Tongze Biotech Co., Ltd.


Why choose our Hydroxychloroquine Powder?
1.AFTER SALES
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Customized Labelsand packageOEM /ODM service
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Packaging & Shipping
Packaging: 25kg/bag or according to client request
Delivery Detail: 1~2 weeks after confirm order.Some of the products can be supplied within 7 days on the strength of EDC warehouse.


FAQ
Q1: What service can you provide?
A:We can provide very competitive prices and very good service to our clients all over the world.
Q2: Can you do customized?
A:We can make the products as per customers' requested products and quantity
Q3:Can we have samples for development?
A:Yes we can provide free samples (small quantity) to you, but the freight cost on buyer's account.
Q4:What is the normal lead time?
A:1. For stock products, we will send goods to you within 2-3 days after we receive your payment.
2. For customized products, generally the delivery time is around 30 days after we receive your payment.

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