What are the benefits of Cycloastragenol?
Cycloastragenol, a triterpene saponin compound, is mainly obtained through the hydrolysis of Astragaloside IV. It is an effective telomerase activator that can increase cell growth and induce CREB phosphorylation.
It usually appearance is crystalline powder.


What are the benefits of Cycloastragenol?
1.Antioxidation
By activating the Nrf2/ARE pathway, it enhances superoxide dismutase activity. This effect can be seen before cardiac surgery. Because the injection of cycloastragenol can reduce oxidative damage to myocardial cells.
2.Anti-inflammatory
Cycloastragenol can relieve chronic inflammation by inhibiting inflammatory factors.
It can assist in the intervention of hyperlipidemia and diabetes, protect the cardiovascular and cerebrovascular system and liver, and improve metabolic syndrome.
3.Regulate immunity
By enhancing macrophage activity, the body's antiviral and anti-infection capabilities are improved, which can be better reflected in people with low immunity.
4.Improve skin health
Promoting collagen synthesis and reducing the degradation of collagen by matrix metalloproteinases achieve anti-wrinkle effects, enhancing lipid production in the stratum corneum, improving problems such as eczema and sensitive skin, and making the skin smoother and more elastic.
5.Anti-aging
Telomerase activation, prolonging telomeres (protective structures at the ends of chromosomes), and slowing down replicative senescence of cells. It can also inhibit the release of pro-inflammatory factors (such as IL-6, TNF-α) and delay tissue aging.

Side effects of Cycloastragenol
1.Common side effects include mild bloating, nausea, and diarrhea. These symptoms are more pronounced when taking cycloastragenol products on an empty stomach.
When using external skin care products, sensitive skin will develop red spots and itching.
2.Potential risks for special groups,including Pregnant/lactating women, children and adolescents, patients with liver and kidney diseases, and patients with rheumatoid arthritis and lupus erythematosus should not use this product.
Reference
1."A natural product telomerase activator as part of a health maintenance program."Rejuvenation Research, 14(1), 45-56
2.Cycloastragenol suppresses oxidative stress and inflammation via Nrf2/HO-1 signaling in LPS-stimulated macrophages."International Journal of Molecular Sciences, 20(3), 702.
3.Potential immunomodulatory effects of cycloastragenol in autoimmune diseases."Journal of Ethnopharmacology, 164, 265-272.
4.Cycloastragenol enhances collagen production in human dermal fibroblasts through TGF-β/Smad pathway."
Journal of Cosmetic Dermatology, 19(10), 2648-2654.




