What is the use of aniracetam?

Aniracitam is a brain function improving drug belonging to the "racitan" drug family. Mainly acting on the cerebral cortex, it can enhance brain protein synthesis and improve brain function by promoting the utilization of phospholipids and amino acids in the brain.

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1.Enhance cognition

By regulating AMPA-type glutamate receptors, it enhances nerve signal transmission and can promote the synthesis of acetylcholine in the brain, which is an important neurotransmitter closely related to learning and memory.

In the elderly population, it can increase long-term memory formation and slow down the decline of memory in the elderly.

2.Protecting brain nerves

If there has been a brain injury, such as a concussion, taking medications containing aniracetam may support the repair and regeneration of brain cells.

By inhibiting lipid peroxidation, reducing the damage of free radicals to the neuronal membrane structure, protecting neurons from secondary damage, and creating favorable conditions for glial cells to repair myelin, thus supporting neuronal survival and synaptic remodeling.

3.Regulate emotions

It is mainly reflected in the two aspects of anti-depression and anti-anxiety.

1)By inhibiting overexcited neuronal activity, it reduces the excessive response of the amygdala in the anxiety-related brain area, regulates the glutamatergic system, and reduces the abnormal connection between the prefrontal cortex and the limbic system.It often manifests itself in anxiety caused by excessive excitement.

2)Aniracetam can promote synaptic plasticity in patients with cognitive impairment due to mild to moderate depression, which is often accompanied by hippocampal atrophy and synaptic loss. This condition is often seen in public figures, school bullies, and around pregnancy.

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1.Common side effects

These may include headache, gastrointestinal upset (nausea, diarrhea), insomnia or sleep disturbances, anxiety or irritability.

1)Aniracetam is a fat-soluble drug. It needs to be taken with fat for slow absorption. Fasting may cause a sudden drop in blood drug concentration.

2)Patients with gastrointestinal dysfunction are more likely to experience gastrointestinal discomfort when taking it in combination with lecithin and donepezil.

3)If medication is taken in the evening or at night, some people may experience circadian rhythm disorders, and the products of drug metabolism may continue to affect sleep quality.

4)Long-term and high-dose use can cause nervous fatigue, and if you have anxiety disorders, the symptoms will be aggravated and induce panic.

2.Rare adverse reactions

Sensitivity to aniracetam or excipients (such as magnesium stearate), allergic constitution may cause rash and difficulty breathing.

Patients with cardiovascular disease may experience blood pressure fluctuations.

3. Risks for special groups

Patients with impaired liver and kidney function, or patients with a history of epilepsy or convulsions may experience worse symptoms.

Pregnant and lactating women are prohibited from using this product

When you first start taking this type of drug, you need to start with a low dose and gradually increase the dose. You need to take it in divided doses. You can take it with fatty foods (nuts, beef) to slow down the absorption rate. You need to stop taking it after 6-8 weeks, or stop taking it according to your doctor's advice.

1.Plaschke, K., et al. (1999). Neuroprotective effects of aniracetam in a rat model of transient focal cerebral ischemia. European Journal of Pharmacology, 375(1-3), 227-234.

2.Cumin, R., et al. (1982). Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. Psychopharmacology, 78(2), 104-111.

3.Yamada, S., et al. (1999). Effects of aniracetam on cognitive function and regional cerebral blood flow in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 10(3), 198-205.

4.Malykh, A. G., & Sadaie, M. R. (2010). Piracetam and piracetam-like drugs: From basic science to novel clinical applications to CNS disorders. Drugs, 70(3), 287-312.

5.Winblad, B. (2005). Piracetam: A review of pharmacological properties and clinical uses. CNS Drug Reviews, 11(2), 169-182.