Ceramide Powder

Ceramide is a family of waxy lipid molecules. The ceramide molecule is composed of a sphingosine molecule and a fatty acid molecule. Ceramides have a relatively high concentration in the cell membranes of eukaryotic cells because they are components of sphingomyelin, the main component of the phospholipid bilayer.

1. Natural extraction method

The naturally extracted ceramides are derived from animals and plants. It originates from the brains of animals with a risk of disease, so it cannot be used in cosmetics. The extraction methods of plants are limited by the growth cycle and season of plants, and the yield is relatively low.

2. Chemical synthesis method

The main chemically synthesized ones are pseudo-ceramides, which have similar structures and functions to ceramides and can be applied in cosmetics. A variety of pseudo-ceramides have been successfully synthesized.

3. Microbial fermentation method

Microbial fermentation is a commonly used method for preparing ceramides in recent years. That is, Pichiaciferrii or Saccharomyces cerevisiae are fermented under certain conditions to obtain tetracetyl sphingosine (TAPS), and then deacetylated to obtain sphingosine. Add fatty acids to synthesize substances such as ceramides.

Meanwhile, for these three methods, the content of natural extraction is relatively low, ranging from 1 to 10%. If it is necessary to extract a high content of over 95%, the ceramide precursor plant sphingosine should be biologically fermented and then synthesized. At the same time, with a high content of 95%, ceramides are classified into different types such as ceramide NP1, ceramide NP2, ceramide 111, ceramide 111B, ceramide AP, ceramide V1, and ceramide EOP. Meanwhile, Xi 'an Tongze can provide all these types of products. Welcome to consult.

Ceramide is an important lipid molecule that is widely present in the cell membranes of living organisms, especially in high concentrations in the stratum corneum of the skin.

1.Used in the of Daily cosmetics

Ceramide is the main component of lipids in the stratum corneum of the skin. It can enhance the skin barrier function, reduce water loss, and improve dry and sensitive skin. It is used to repair skin damage caused by environmental stimuli (such as ultraviolet rays, pollution) or excessive cleaning.

It is often added to face creams, essences and creams.

2.Used in the field of medicine

To help repair damaged skin barriers, especially for dermatitis, eczema and psoriasis, ointments or medical dressings containing ceramides can be used.

Ceramides are involved in cellular signal transduction and are related to the research on mechanisms associated with cancer and neurodegenerative diseases. At the same time, they may also affect insulin resistance and neuropathy

3. Used in the field of Food health product

To improve the possibility of skin health, oral supplements of collagen combined with ceramides can be taken

1.Skin barrier and moisturizing

Ceramides, along with cholesterol and fatty acids, form the "brick wall structure" of the stratum corneum of the skin, filling the gaps between keratinocytes and preventing water loss and the invasion of external irritants. By forming a lipid bilayer, it adsorbs water molecules and maintains the moisture content of the skin. At the same time, it can repair damage. Ultraviolet rays, excessive cleaning or chemical irritation can damage the skin barrier. Supplementing ceramides can accelerate the recovery of the stratum corneum and reduce redness and flaking.

2.Anti-aging and elasticity maintenance

The loss of ceramides can lead to dry and loose skin. After supplementation, it can promote the production of collagen, reduce fine lines and enhance skin elasticity. Meanwhile, some ceramides can enhance the effect of antioxidant components and resist free radical damage.

3.Anti-inflammatory and metabolic regulation

Inhibit the release of inflammatory factors (such as IL-6, TNF-α), and alleviate problems such as skin redness, swelling, and acne. It is involved in the insulin signaling pathway and may affect the progression of diabetic complications and neuropathy.

4.Adjuvant therapy for skin diseases

It is used for eczema, psoriasis and other diseases, reducing the risk of allergen penetration and bacterial infection by repairing the barrier. Promote the migration of epidermal cells and accelerate the recovery of wounds

The effect of using ceramides alone is limited. They need to be used in combination with cholesterol (in a 3:1 ratio) and fatty acids (such as in a "triple lipid" formula). The effect of ceramides can only be brought into play when used in combination.

Type differences: Ceramides with different structures (such as Ceramide NP, AP) target different issues (moisturizing, anti-aging, etc.).

Stability: Prone to oxidation, encapsulation techniques (liposomes, microcapsules) are often required in skin care products to maintain their activity.

The role of ceramides is not limited to being "moisturizing components", but they are also important molecules that connect skin health, disease treatment and biotechnology. They have great potential in precision medicine and new materials in the future.

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