What are the benefits of diosmin?

Diosmin naturally occurs in the peels or leaves of some citrus plants (such as lemons, bitter oranges). Hesperidin extracted in large quantities from citrus peels, and hesperidin is enzymatically oxidized to make diosmin.This method is efficient and low in cost, which meets the current market's delicate esoline. It not only has the biological activity of natural flavonoids, but also meets the large-scale needs of drugs. Therefore it is a natural flavonoid compound.

1.Improve venous function

Long-term sitting and standing for a long time can cause leg discomfort. Diosmin can promote blood flow, reduce venous pressure, and relieve this symptom. At the same time, it can reduce the risk of venous dilation and deformation, and effectively prevent and alleviate varicose veins.

2.Anti-inflammatory and swelling

It can inhibit inflammation and reduce vascular leakage Inhibition of inflammation is manifested in leg swelling, pain, redness or fever in the skin, as well as varicose veins and joint surgery, diosmine can reduce the inflammatory response of the venous wall, relieve edema and soreness of lower limbs, relieve postoperative inflammatory edema, accelerate tissue fluid reflux, and shorten recovery time. Reduces vascular leakage, which is commonly found in acute hemorrhoids, swelling, pain, and bleeding of the anal hemorrhoids. It relieves hemorrhoid congestion and blood oozing.

3.Antioxidant effects

Reduce the attack of free radicals on collagen in endothelial cells and promote normal vasoconstriction and diastolic. Diosmine reduces this attack by antioxidant, maintaining venous elasticity and strength. At the same time, it inhibits the oxidative activation of inflammation and reduces its persistent damage to blood vessels.

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1.The most common gastrointestinal discomforts are nausea, bloating, abdominal pain, diarrhea or constipation. These side effects often occur when taking medication on an empty stomach, long-term and overdose, or if you have a history of gastritis or gastric ulcers, they may irritate the gastric mucosa.

2.Rare adverse reactions

Rare adverse reactions, allergic reactions, and a small amount of jaundice. It occurs in people who are allergic to citrus plants, flavonoids or drug excipients, and then allergic reactions occur. As well as those with liver insufficiency, they will increase the risk of hepatitis, cirrhosis, etc.

3.High-risk population

Elderly patients have slow metabolism and are more likely to have side effects.Pregnant women/lactation periods need to follow the doctor's advice.

4. Risks for special groups

Pregnant women, lactating women, the elderly and those with impaired liver and kidney function.

1)Pregnant women, breastfeeding women, and those with impaired liver and kidney function should use it with caution and follow the doctor's advice

2)Elderly people should be careful not to use it with antiarrhythmic drugs, as it may cause palpitations.

Recommended dosage: Especially for patients with a history of heart disease, you can take 5 mg at a time, and monitor your electrocardiogram at all times.

3)Children aged 2 to 12 years old should use syrup, which is easy to control the amount of consumption. After taking it, monitor whether the child is overexcited or sleepy.

If mild gastrointestinal discomfort occurs, you need to take it after meals and use it in batches to reduce the dose.

If you have an allergic reaction, you should stop using it or follow the doctor's advice.

1.Diosmin Attenuates Oxidative Stress and Inflammation in Experimental Colitis Journal of Pharmacology and Experimental Therapeutics, 2012, 343(2): 411-422.

2. Clinical Benefits of Diosmin in Chronic Venous Disease: A Randomized Controlled Trial Phlebology, 2008, 23(1): 18-24.

3. Diosmin in the Management of Hemorrhoids: A Systematic Review World Journal of Gastroenterology, 2020, 26(48): 7605-7618

4.Diosmin AND (venous insufficiency OR hemorrhoids OR antioxidant) https://pubmed.ncbi.nlm.nih.gov