What is Retinoic Acid Powder?

Retinoic acid Powder is a commonly used drug in dermatology. It is an intermediate product of vitamin A (vitamin methanol) metabolism in the body. It mainly affects bone growth and epithelial metabolism, can promote the proliferation and renewal of epithelial cells, and can inhibit the proliferation and differentiation of keratinocytes. to restore hyperkeratosis to normal, so it has a certain therapeutic effect on many diseases with complete keratosis, incomplete keratosis, and hyperkeratosis, and can treat a variety of skin diseases. Topical application penetrates the skin quickly and can significantly increase epithelial cell renewal. This class of drugs has a strong and rapid inhibitory effect on the secretion of sebaceous glands, which can reduce sebum secretion. In addition, this product also has anti-tumor, wound healing and anti-infection effects.

1.Retinoic Acid Powder is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc.
2.Retinoic Acid Powder can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3.Retinoic Acid Powder is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.

1.This product is contraindicated for those who are allergic to it, those allergic to vitamin A derivatives, patients with acute or subacute dermatitis, eczema skin diseases, and pregnant women.

2.People with allergic constitutions should use with caution.

3.Lactating women should stop breastfeeding during the medication period, and women of childbearing age are strictly prohibited from getting pregnant during the medication period. Use with caution in children.

4.This product should be kept away from eyes and other mucous membranes (such as the mouth, nose, etc.). It is not suitable for use on areas of skin folds and skin ulcers.

5.If there is a burning sensation, itching, redness or swelling at the application site, stop using the medicine immediately, wash the local area with the medicine, and consult a doctor if necessary.

6.It is used to treat acne. The condition may temporarily worsen in the first few weeks, but treatment should continue for more than 6 weeks to achieve the maximum therapeutic effect.

7.This product should not be used on a large scale, and the daily dosage should not exceed 20g.

8.During the medication period, do not use any other drugs, cosmetics or cleansers that may cause skin irritation or damage, as this may aggravate skin reactions, increase drug absorption and cause adverse systemic reactions.

9.Sunlight can intensify the irritation of retinoic acid to the skin, leading to its decomposition. Animal experiments suggest that retinoic acid can enhance the carcinogenic ability of ultraviolet rays. Therefore, this product is most suitable for application at night and before going to bed. During the treatment process, sun exposure should be avoided or shading measures should be adopted.

1.There is a risk of increasing photosensitivity when used in combination with photosensitive drugs.

2.When used together with detergents such as soap, desquamation agents (such as benzoyl peroxide, resorcinol, salicylic acid, sulfur, etc.), ethanol-containing agents, isotretinoin, etc., it can aggravate skin irritation or dryness. Therefore, it must be used with caution.

3.Is it combined with cimetidine, cyclosporine and dilthiosulfate? When used in combination with verapamil, ketoconazole, etc., it may cause an increase in the blood concentration of this product and may lead to retinoidosis.

4.When used in combination with pentobarbital, phenobarbital and rifampicin, it may cause a decrease in the blood concentration of this product.

5.This product can affect the hepatocellular pigment P450 enzyme system, leading to changes in drug concentration in the blood.

6.Taking oryzanol, vitamin B1, vitamin B6 and other drugs simultaneously can alleviate or eliminate adverse reactions such as headache caused by this product. Information on the pharmacological effects, pharmacokinetics, pharmacodynamics, indications, drug interactions and side effects of retinoic acid, A commonly used dermatological drug, was edited by Yao Yao of chemcialbook (September 24, 2015).

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