Pure 99% Theobromine Powder

Theobromine is a naturally occurring methylxanthine alkaloid primarily found in cacao beans, cocoa, dark chocolate, tea leaves and kola nuts. Theobromine powder is the purified, solid powdered form of this compound manufactured for research, food additive and raw material usage.

1. Basic Chemical Information

Chemical Name: 3,7-Dimethylxanthine

Molecular Formula: C₇H₈N₄O₂

Physical characteristics: White crystalline powder, slightly bitter taste, sparingly soluble in cold water and soluble in hot water.

Purity of commercial powder: Usually ≥99% as tested by HPLC.

Cardiovascular regulation It dilates blood vessels, lowers peripheral vascular resistance, promotes blood circulation and has mild hypotensive effects. It can also enhance myocardial contraction.

Diuretic effect It inhibits tubular reabsorption of water and electrolytes, increasing urine output and reducing excess fluid retention in tissues.

Respiratory tract relaxation It relaxes the smooth muscles of the bronchi, relieves bronchospasm, and helps ease mild asthma and shortness of breath.

Mild central nervous system stimulation It delivers gentle stimulant effects on the brain, much milder than caffeine. It boosts alertness without causing severe nervousness or insomnia.

Lipid metabolism regulation It accelerates fat decomposition and lipolysis, which makes it widely studied in weight-management research.

Food & beverage raw material Used to formulate chocolate-flavored food, energy drinks and functional food supplements.

Pharmaceutical intermediate & research reagent Applied in preclinical studies of diuretic, anti-asthma and cardiovascular health products.

Cosmetic raw material Added to skincare formulas to promote microcirculation and reduce subcutaneous edema and cellulite.

Disclaimer

This dosage guideline applies only to pure theobromine powder for dietary supplement use. This product is not a prescription drug. All users should start with a low dose to test individual tolerance. This powder is strictly forbidden for animal feeding, especially dogs and cats.

1. Oral Dosage for Healthy Adult Humans

Basic Maintenance & Mild Energy Support

Starting dose: 100 mg – 250 mg per day, taken once in the morning.

Suitable for improving focus, promoting circulation and relieving mild fatigue.

Standard Supplement Dosage (Most Common)

250 mg – 400 mg per day, single oral dose.

Taken on an empty stomach with water, 30–60 minutes before meals or workouts.

High-Dose Research & Sports Nutrition

Maximum safe daily oral dose: 500 mg per day.

Doses exceeding 600 mg greatly increase risks of palpitations, insomnia and stomach irritation.

Do not split into multiple high doses; take the full amount once daily.

Combined Stack with Caffeine

Theobromine: 150 mg + Caffeine: 50–100 mg per serving to avoid excessive central stimulation.

2. Experimental Animal Dosage (For Lab Research Only)

Oral Administration for Rodents

Daily oral dose: 5 mg/kg to 15 mg/kg body weight.

Intraperitoneal Injection

Single dose: 3 mg/kg – 8 mg/kg body weight.

3. Pharmaceutical Experimental Dosage (Preclinical Study)

For cough suppression and bronchodilation trials: 25 mg, three times daily (75 mg total per day).

4. Administration Notes

Do not take after 4 PM to prevent sleep disturbance.

Pure crystalline powder must be weighed with a precision milligram scale; volume measurement is inaccurate.

Avoid long-term continuous use above 400 mg daily.

People with heart disease, hypertension, gastric ulcers and pregnant women should not use this powder without physician approval.

5. Upper Toxicity Limit

Acute oral doses above 1000 mg may trigger nausea, arrhythmia, tremor and electrolyte loss.

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Pure theobromine powder has high concentration. Accidental overdose is far easier than eating natural chocolate.

Do not take it together with caffeine or other xanthine substances, as the stimulant effects will be superimposed and greatly raise the risk of side effects.

1. Mild Adverse Reactions (from moderate overconsumption)

Gastrointestinal discomfort: nausea, stomach ache, vomiting and diarrhea. Theobromine irritates gastric mucosa when taken on an empty stomach.

Central nervous system excitation: anxiety, jitters, irritability, difficulty falling asleep and frequent wakefulness at night.

Cardiovascular symptoms: mild tachycardia, palpitations and elevated blood pressure.

2. Severe Side Effects (caused by high excessive intake)

Severe heart rhythm disorders including arrhythmia.

Severe nervous overexcitation: muscle tremors, vertigo and even convulsions.

Excessive diuresis leading to electrolyte loss, dehydration and muscle cramping.

Acute poisoning may cause hypotension, breathing abnormalities.

3. Long-term Continuous High-Dose Use

Chronic overconsumption may lead to persistent sleep disorders, recurring heart palpitations and chronic digestive problems. Physical dependence can also develop gradually.

4. Special Populations and Risks

Pregnant women: Excessive intake may affect fetal development, so high doses should be avoided.

People with hypertension, heart disease and arrhythmia: Theobromine dilates blood vessels and stimulates the heart, which may worsen symptoms.

Individuals with peptic ulcers: It will aggravate gastric irritation.

Pets (dogs, cats): Theobromine cannot be metabolized quickly in their bodies. Even small amounts may result in fatal poisoning.

Common Side Effects

Cardiovascular reactions: Transient hypotension, flushing, tachycardia. These usually occur shortly after administration and are mild and reversible.

Gastrointestinal symptoms: Nausea, vomiting, abdominal distension and mild diarrhea.

Local reactions: Redness, swelling or soreness at the injection site for parenteral use.

Less Common Side Effects

Respiratory discomfort: Mild cough, transient shortness of breath.

Systemic symptoms: Dizziness, fatigue, headache.

Metabolic changes: Slight decrease in blood glucose in individual patients.

Rare but Severe Adverse Reactions

Severe hypotension: May lead to syncope, especially in patients with unstable cardiovascular conditions.

Hypersensitivity reactions: Rash, urticaria, pruritus; very rarely anaphylaxis.

Severe gastrointestinal disturbances: Severe vomiting or persistent abdominal pain.

Special Notes

Side effects are generally dose-related. Adverse reactions are more likely to appear if the infusion rate is too fast or the dose is excessive.

Patients with pre-existing heart disease, hypotension or gastrointestinal disorders need close monitoring during medication.

Any persistent or severe discomfort must be reported to medical staff immediately.

Other Nootropics Raw Material Also Available

Delivery Time:Around 3-5 workdays after your payment.

Package:1kg/aluminium foil bag;25Kgs in fiber-drums with two-plastic bags inside

Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum

Drum Size & Volume:I.D.42cm × H52cm,0.08 m³/Drum

Storage:Stored in dry and cool place,keep away from strong light and heat.

Shelf Life:Two years when properly stored.

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